摘要
目的通过对96例药品不良反应/事件报告进行统计分析,为临床合理用药提供参考。方法采用回顾性研究方法,对2012年我院上报的96例药品不良反应/事件报告,分别从药物种类、抗菌药物类别、临床表现、给药途径及患者年龄等方面进行系统分析。结果 96例药品不良反应/事件报告中,涉及药品45种,其中抗菌药物有关的药品不良反应/事件最多(50例,占52.08%);静脉滴注给药发生引起的最多(88例,占91.67%)。60岁以上老人发生率高于其他年龄段43例(占44.79%),严重药品不良反应/事件4例(占4.17%)。药品不良反应/事件临床表现最为常见的是皮肤及其附件损害(77例,占80.21%),其次是心血管系统损害等。结论应重视药品不良反应/事件,合理使用抗菌药物,以减少和避免药品不良反应/事件的发生。
Objective To analyze the characteristics of the adverse drug reactions/events (ADR/ADE)and to provide reference for clinical rational drug use. Methods By a retrospective study, 96 cases reported in our hospital in 2012 were analyzed in respect of drug species, categories of antimicrobial drugs, clinic manifestations, ways of administration and ages of the patients. Results Altogether 45 kinds of drugs involved ADR, in which the antimicrobial drugs took the lead (50 cases) which amounted to 52.08% of the total. 88 cases (91.67%)were induced by intravenous route of administration of the total, with elder ≥60 years showing higher proportion(43 cases, 44.79%); 4(4.17%)were regarded as serious cases. The main clinic manifestations of ADR/ADE were skin and local lesion, then cardiovascular system damage and etc. Conclusion Great importance should be attached to the reporting and mornitoring on ADR/ADE and rational use of drugs in order to avoid or reduce the occurrence of ADRs/ADEs.
出处
《中国医药指南》
2014年第7期29-31,共3页
Guide of China Medicine
关键词
药物不良反应
事件
抗菌药物
分析
Adverse drug reations
Anti-microbial drugs
Analysis