胃癌D2根治术后淋巴结转移率与预后的关系

Relationship between lymphnodes metastatic rate and prognosis after D2 radical gastrectomy forgastric cancer

目的探讨胃癌D2根治术后淋巴结转移率（MLR）与预后的关系。方法回顾性分析2005年8月至2008年7月接受D2根治术的203例胃癌患者的临床病理资料。结果单因素分析显示：MLR、肿瘤发生部位、浸润深度、远处转移及淋巴结转移数目均为胃癌患者预后的独立、有效的预测指标（P〈0．05）。多因素分析表明：MLR是淋巴结转移胃癌患者预后的一项独立、有效的预测指标（P〈0．05），MLR与患者的5年总体生存率呈显著负相关（P〈0．05）。结论MLR是影响胃癌患者预后的一项独立预测指标，其预测效果比淋巴结转移数目更准确、客观。

Objective To investigate the relationship between lymphnodes metastatic rate and prognosis after D2 radical gastrectomy for gastric cancer. Methods The clinical and pathological data of 203 patients with gastric cancer who underwent D2 radical gastrectomy, from August 2005 to July 2008, were analyzed retrospectively. Results The univariate analysis revealed that MLR, tumor location, depth of invasion, distant metastasis and number of metastatic lymph nodes were all independent and ef- fective predicting indexes for gastric cancer （P 〈 0.05 ）. The multivariate analysis indicated that MLR was an independent and effective prognosis predictor for gastric cancer patients with metastatic lymph nodes （ P 〈 O. 05 ）. MLR was significantly negative correlated with the 5-year overall survival rate （OSR） （P 〈 0.05 ）. Conclusions MLR is an independent and effective prognosis predictor for patients with gastric cancer, and the predicting effect of MLR is more accurate and objective than that of the number of metastatic lymph nodes.