摘要
为提高自制的纳米掺锶羟基磷灰石(Sr-HAP)粒子的分散性和蛋白吸附能力,采用低温等离子体表面改性接枝技术,在Sr-HAP粒子表面接枝了丙烯酸(AAc),并对接枝了丙烯酸的纳米粒子Sr-HAP-AAc进行了傅里叶变换红外光谱、热重分析和悬浮稳定性的表征研究.结果发现:SrHAP-AAc在水溶液中的分散性增强和稳定性变好,并且对目标蛋白的吸附量明显增大.
In order to improve the dispersion and protein adsorption of home-made strontium-substituted hydroxyapatite （Sr-HAP）nanoparticles, Sr-HAP was modified by low temperature plasma technology and surface of Sr-HAP was grafted with acrylic acid （AAc）. The modified Sr-HAP-AAc was characterized by Fourier transform infrared spectroscopy, thermogravimetric analysis and suspension stability. The results showed that the dispersibility, stability and adsorption to target protein of Sr-HAP-AAc were improved.
出处
《东华大学学报（自然科学版）》
CAS
CSCD
北大核心
2014年第1期1-5,共5页
Journal of Donghua University(Natural Science)
基金
国家自然科学基金资助项目(51203020)
上海市自然科学基金资助项目(11ZR1400500)
教育部留学回国人员科研启动基金资助项目
中央高校基本科研业务费专项资金资助项目
关键词
掺锶羟基磷灰石
等离子体
接枝改性
分散性
蛋白吸附
strontium-substituted hydroxyapatite
plasma
graft modification
dispersibility
protein adsorption
