天津市农村40岁以上人群血脂水平与血清肉毒碱棕榈酰基转移酶的相关性研究

Study on the correlation between serum lipid and serum carnitine palmitoyl transferase 1A in rural adults over 40 years in Tianjin

目的了解天津市农村40岁以上人群血脂状况,并分析其与血清肉毒碱棕榈酰基转移酶的相关性。方法采用多阶段整群随机抽样,从天津市农村地区抽取719名40岁以上的人群,采集空腹静脉血测定血清总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、肉毒碱棕榈酰基转移酶1A(CPT1A),对结果进行分析。结果血脂异常率为46.73%(336/719),男性为48.22%(163/338),女性为45.41%(173/381),差别无统计学意义。简单线性相关分析显示,CPT1A与TC、LDL-C的相关系数r分别为0.123和0.130(P<0.01);经多元线性回归分析后,只有LDL-C与CPT1A呈相关关系(P<0.01)。结论天津农村40岁以上人群血脂异常率偏高,血脂水平与血清肉毒碱棕榈酰基转移酶关系密切。

Objective To explore the status of serum lipids and analyze its relationship with carnitine palmitoyl transferase 1A （CPT1A） in rural people over 40 in Tianjin, China. Methods By cluster multi-stratified sample of 719 people over 40 was investigated with a questionnaire from rural areas in Tianjin. And finally draw a conclusion based on data analysis from fasting blood and measured total cholesterol （TC）, triglyceride （TG）, high density lipoprotein cholesterol （HDL-C） and CPT1A. Results In this research, the rate of dyslipidemia was 46.73% , in which 48.22 percent male and 45.41 percent female, a nonsignificant difference. CPT1A correlated with TC, LDL-C were 0. 123 and 0. 130, with simple linear regression, and there was only significant difference between LDL-C and CPT1A by multiple regression analysis. Conclusion There is a high rate of dyslipidemia among the rural people over the age of 40 in Tianjin, and the CPT1A is closely associated with serum lipid.