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以肠道菌群为靶点论2型糖尿病的可逆性 被引量：1

Reversibility of Type 2 Diabetes: Taking Intestinal Flora as a Target
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摘要 2型糖尿病是一种常见的慢性代谢性疾病,临床上可以通过严格的饮食控制,尤其是以中医"药食同源"等理论为指导,辨证施治,调整肠道菌群,降低体内毒副作用,重建胰岛功能,达到逆转的可能。 Type 2 diabetes is a common chronic metabolic tern identification and treatment determination, adjustment of and reconstruction of islet function. disease and can be reversed by strict diet control, pat- intestinal flora, reduction of toxicity and side reactions
作者 秦培钧 李同侠 张宁
机构地区 中国中医科学院研究生院 中国中医科学院望京医院
出处 《中医杂志》 CSCD 北大核心 2014年第7期558-562,共5页 Journal of Traditional Chinese Medicine
关键词 2型糖尿病 肠道菌群 高脂饮食 消渴 type 2 diabetes intestinal flora fat diet dispersion-thirst
分类号 R587.1 [医药卫生—内分泌]
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参考文献33

  • 1Grover JK, Rathi SS, Vats V. Amelioration of experimental diabetic neuropathy and gastropathy in rats following oral administration of plant ( Eugenia jambolana, Mucuna pru- riens and Tinospora cordifolia) extracts [ J ]. Indian J Exp Biol,2002,40 ( 3 ) : 273 - 276.
  • 2Mukhopadhyay P, Basu AK. Management of diabetic gastro- paresis[J]. J Indian Med Assoc,2005,103(3) :184- 186.
  • 3Lira EL, Hollingsworth KG, Aribisala BS, et al. Reversal of type 2 diabetes : normalisation of beta cell function in asso- ciation with decreased pancreas and liver triacylglycerol [ J]. Diabetologia,2011,54(10) :2506 - 25t4.
  • 4Hotamisligil GS. Inflammation and metabolic disorders [ J ]. Nature ,2006,444 (7121) :860 - 867.
  • 5Backhed F, Ding H, Wang T, et al. The gut microbiota as an environmental factor that regulates fat storage [ J ]. Proc Nat Acad Sci USA ,2004,101 (44) : 15718 - 15723.
  • 6Turnbaugh PJ, Ley RE, Mahowald MA, et al. An obesity- associated gut microbiome with increased capacity for energy harvest [ J ]. Nature,2006,444 (7122) : 1027 - 1131.
  • 7Ley RE, Turnbaugh PJ, Klein S, et al. Microbial ecology: human gut microbes associated with obesity [ J ]. Nature, 2006,444(7122) : 1022 - 1023.
  • 8Backhed F, Manchester JK, Semenkovich CF, et al. Mechanisms underlying the resistance to diet-induced obesity in germ-free mice [ J ]. Proc Nat Acad Sci USA, 2007,104 (3) : 979 - 984.
  • 9Samuel BS, Shaito A, Motoike T, et al. Effects of the gut mi- crobiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41 [ J]. Proc Nat Acad Sci USA .2008.105 (43) : 16767 - 16772.
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中医杂志
2014年 第7期

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