摘要
目的探讨益肾化湿颗粒联合血液透析对尿毒症患者低密度脂蛋白(LDL)、甲状旁腺素(iPTH)、C反应蛋白(CRP)和钙磷乘积改善效果。方法选择中南大学湘雅三医院2010年3月至2013年3月收治的尿毒症患者83例为研究对象,依据临床治疗方法不同将患者分为治疗组(42例)和对照组(41例)。治疗组给予益肾化湿颗粒联合血液透析治疗;对照组给予单纯的血液透析治疗。对患者治疗前后患者血磷、血钙以及磷钙乘积、LDL、iPTH、CRP等相关检测指标进行比较分析。结果两组患者治疗后血磷、血钙、磷钙乘积、LDL、iPTH和CRP均有不同程度改善,差异有统计学意义(P<0.05)。治疗后LDL、iPTH、CRP和钙磷乘积比较,治疗组明显优于对照组,差异有统计学意义(P<0.05)。结论益肾化湿颗粒联合血液透析对尿毒症患者LDL、iPTH、CRP和钙磷乘积有明显的改善作用。
Objective To investigate the effect of Yi Shen Hua Shi Granules combined with hemodialysis on low density lipoprotein （LDL） ,parathyroid hormone （iPTH） ,C reactive protein （CRP） and calcium-phosphate prod-uct in patients with uremia .Methods A total of 83 patients with uremia in the Third Xiangya Hospital of Central South University were enrolled and divided into therapy group （42 cases） ,receiving combined therapy of Yi Shen Hua Shi Granules and hemodialysis ,and control group （41 cases） ,receiving hemodialysis alone .Serum phosphorus , calcium and calcium-phosphorus product ,LDL ,iPTH ,and CRP were compared between the two groups before and after treatment .Results In the two groups ,serum phosphorus ,calcium and calcium-phosphorus product ,LDL ,iPT H and CRP were significantly improved compared with before treatment （P＆lt;0 .05） .After treatment ,LDL ,iPTH ,CRP and calcium-phosphate product of treatment group were all better than control group （P＆lt;0 .05） .Conclusion The treatment of Yi Shen Hua Shi Granules combined with hemodialysis could significantly improve LDL ,iPT H ,CRP and calcium-phosphate product in patients with uremia .
出处
《检验医学与临床》
CAS
2014年第6期768-769,772,共3页
Laboratory Medicine and Clinic
