纤维蛋白原水平与冠状动脉病变程度的相关性研究

STUDY OF THE CORRELATION BETWEEN FIBRINOGEN LEVES AND THE LESION DEGREE OF CORONARY ARTERY

目的 探讨纤维蛋白原水平与冠状动脉病变程度的关系。方法 1 1 4例按冠状动脉造影结果分为正常组、病变组及不同程度病变组 ,对其纤维蛋白原水平进行统计学分析。结果 正常组与病变组间、正常组与不同程度病变组间纤维蛋白原水平有显著性差异 (P <0 0 5 ,P <0 0 1 ) ,病变组内部两两比较显示有递增趋势。结论 纤维蛋白原水平与冠状动脉病变程度密切相关 ,对于冠心病的防治有重要意义。

Objective to investigate the correlation between fibrinogen level and the degree of coronary arterial stenosis.Methods 114 cases who had undergone diagnostic coronary angiography were divided into normal group and lesion group,of whom subdivision was performed on basis of their lesion degrees.Statistical analysis was carried out about their fibrinogen levels.Results There was significant difference in fibrinogen level between the normal group and the lesion group(P<0.05)and the same difference was shown also between the normal group and the lesion group with different degress(P<0.01).The fibrinogen level within the lesion group showed a increasing tendency.Conclusion There exists a close correlation between fibrinogen level and the lesion degree of coronary arterial stenosis,which is of great significance to the prevention and the treatment of coronary heart disease.