两种缓释剂联合治疗急性智齿冠周炎的疗效观察

Observation on clinical effect of two kinds of sustained-release agents on acute pericoronitis

目的观察两种缓释剂盐酸米诺环素软膏、甲硝唑棒联合治疗急性智齿冠周炎的临床治疗效果。方法选择第三磨牙发生冠周炎的患者110例,随机分为治疗组和对照组各55例。治疗组在进行常规盲袋冲洗后将2%盐酸米诺环素软膏及1 cm长甲硝唑棒置入盲袋内,3 d后复诊;对照组仅进行常规冲洗,局部导入1%碘甘油,1次/d,第4天观察两组临床效果。结果治疗组和对照组的总有效率分别为94.5%和63.6%。与对照组比较,治疗组患者冠周疼痛和肿胀的消退时间明显缩短(P<0.01)。结论应用盐酸米诺环素软膏、甲硝唑棒联合治疗急性智齿冠周炎具有明显效果。

Objective To observe the clinical effect of two kinds of sustained-release agent, including minocycline hydrochloride ointment and metronidazole rods, on acute pericoronitis. Methods Selecting 110 patients who had the third molar pericoronitis, randomly dividing them into treatment group and control group, 55 cases per each. During the treatment group, after conventionally rinse the blind pouch, put 2%minocycline hydrochloride ointment and 1cm metronidazole stick into it;while during the control group, only routine washing of the blind pouch and partial coating of 1%iodine glycerin, once a day. All these cases were further clinically observed 3 days after treatment. Results The total effective rate of the test group and control group were 94.5%and 63.6%. There was statistic significance before and after the treatment between two groups（P＆lt;0.01）. Conclusion The joint application of minocycline hydrochloride ointment and metronidazole rods on acute pericoronitis has a significant effect.