奥扎格雷钠注射液与低分子肝素钙治疗不稳定型心绞痛的疗效观察

Observation on the curative effect of Ozagrel Sodium Injection and low molecular weight heparin calcium on unstable angina pectoris

目的探讨奥扎格雷钠注射液与低分子肝素钙联合应用在不稳定型心绞痛中的治疗效果。方法选择本院82例不稳定型心绞痛患者,上述患者随机分为观察组和对照组,两组均给予常规治疗,对照组同时给予奥扎格雷钠注射液,观察组给予奥扎格雷钠注射液联合低分子肝素。评定两组疗效,观察血液流变学指标改变情况。结果观察组总有效率为95.0%,对照组总有效率为75.6%,观察组总有效率高于对照组(P<0.05)。观察组治疗后全血粘度高切、全血粘度低切和血液粘度分别与对照组治疗后比较,差异有统计学意义(P<0.05)。结论奥扎格雷钠注射液与低分子肝素钙治疗不稳定型心绞痛效果显著,有助于改善患者血液流变学指标,值得借鉴。

Objective To explore the effect of combined application of Ozagrel Sodium Injection and low molecular weight heparin on unstable angina pectoris. Methods 82 cases with unstable angina patients, the patients were randomly divided into observation group and control group, two groups were given conventional treatment, the control group was treated ozagrel sodium Injection, the observation group was given ozagrel sodium Injection combined with low molecular weight heparin. the efficacy of two groups was evaluated, the changes of blood rheology was observed. Results The total effective rate in the observation group, was 95%, the total effective rate in the control group was 75.6%, the total effective rate in observation groupwas higher than that in the control group （P＆lt;0.05）. The whole blood high shear viscosity, whole blood low shear viscosity and blood viscosity in the observation group after treatment compared with those in the control group after treatment, the difference was statistically significant （P＆lt;0.05）. Conclusion Ozagrel sodium Injection combined with low molecular weight heparin calcium on unstable angina pectoris has significant effect, and may improve the hemorrheology.