摘要
目的:分析我院抗菌药物在国家基本药物制度和抗菌药物专项整治活动实施前后的利用情况,评估我院抗菌药物品种、用药特点、使用合理性受政策利导的的变化情况。方法:对我院2010-2011年抗菌药物用药频度(DDDs)、日均费用(DDC)、药物利用指数(DUI)、金额/DDDs排序位次比、平均治疗日数(ATD)进行统计、分析。结果:随着国家基本药物制度实施,基本药物在我院抗菌药物DDDs排名前10位的抗菌药物中比重增加,DDC在几元至30多元之间,金额/DDDs排序位次比偏高;我院抗菌药物DUI小于1和大于1的情况普遍存在,用药不足和用药过量的情况均不容乐观,ATD与药品说明书的规定疗程比较亦有出入。结论:国家基本药物制度推动了基本药物在医院的使用,基本药物在DDC、金额/DDDs排序位次比上具有显著优势,降低了患者的经济负担;通过抗菌药物分级管理制度,将DUI和ATD配合抗菌药物专项整治活动中对抗菌药物临床应用的点评,可及时发现医师用药方面的弊端,促进临床合理使用抗菌药物。
OBJECTIVE ： To analyze the utilization of antibiotics in our hospital before and after the implementation of Nation- al Essential Medicine System and antibiotics special rectification activities, and to evaluate the changes of antibiotics types, the characteristics and rationality of drug use guided by policies. METHODS： The utilization of antibiotics in our hospital during 2010--2011 was analyzed statistically in respects of DDDs, DDC, DUI, the amount/DDDs sequence ratio and average treatment day （ATD）. RESULTS： Along with the implementation of National Essential Medicine System, the proportion of essential drug in- creased in our hospital among top 10 antibiotics in the list DDDs. DDC of essential medicines was in a few yuan to 30 yuan. The amount/DDDs sequence ratio of essential drugs was high. It was prevailing that DUI of antibiotics was less than 1 and more than 1 in our hospital. Under-medication and overdose was not optimistic. ATD were inconsistent with the treatment course stated in drug package inserts. CONCLUSIONS： National Essential Medicine System promotes the use of essential medicines in hospital. The es- sential medicines have remarkable advantage in DDC and the amount/DDDs sequence ratio, and reduce the economic burden of the patient. Through antibiotics classification management system, DUI, ATD combined with antibiotics special rectification activi- ties could discover the defects of drug use among doctors and promote the clinical rational use of antibiotics.
出处
《中国药房》
CAS
CSCD
2014年第14期1267-1270,共4页
China Pharmacy
