我院2010-2012年医院制剂药物利用研究

Study on the Utilization of Hospital Preparations in Our Hospital from 2010 to 2012

目的:探讨我院医院制剂的定位与发展方向。方法:按照药物利用研究的基本方法,对我院2010-2012年医院制剂的使用量、用药金额、用药频度(DDDs)等进行统计,分析我院医院制剂使用的倾向性。结果:2010-2012年我院制剂品种的配制与使用总体保持稳定。中药制剂用药金额每年均达到全部自制制剂用药总金额70%以上,并显现出明显的集中趋势,以虎杖解毒颗粒、乳腺通络散结颗粒等为代表的特色中药制剂呈现良好增长态势;西药制剂略有萎缩,使用量靠前的部分品种如炉甘石薄荷脑洗剂、复方薄荷脑滴鼻液等使用量有所下降,3年来呈增长趋势的制剂有溴化钠甘草合剂、硫酸镁口服溶液。3年间停止生产的医院制剂有硫酸阿托品滴眼液、复方氯霉素洗剂等4种,主要因为无法购买到原料、使用量少。结论:继续保持现有制剂的稳定生产并积极开发特色中药制剂,既可满足临床患者的用药需求,也是我院制剂生存和发展的方向。

OBJECTIVE： To explore the hospital preparations positioning and development direction of our hospital. METHODS： According to the fundamental method of drug utilization, the amount, consumption sum and DDDs of hospital preparations in our hos- pital from 2010 to 2012 were statistically analyzed to explore the characteristic and orientation. RESULTS： The preparation and utiliza- tion of our hospital preparations remained stable overall during 2010 to 2012. The consumption sum of TCM preparations accounted for more than 70 % of the total and had shown central tendency; the consumption sum and DDDs of the characteristic TCM preparations, such as Huzhang jiedu granules, Ruxian tongluo sanjie granules, had shown good growth trend. The western medicine preparation de- creased slightly; the amount of western medicine preparations which took up the front place in the list of amount had declined, such as Calamine and menthol lotion, Compound menthol nasal drops. The amount of Sodium bromide and glycyrrhiza oral solution and Mag- nesium sulfate oral solution had a tendency to increase. End-of-life preparations were Atropine sulfate eye drops, Compound chloram- phenicol lotion and other 2 drugs, and they were resulted from the supply question of raw materials and low consumption. CONCLU- SIONS： With continue to maintain the stability of existing formulations production, actively developing TCM preparations with charac- teristics, the medication needs could be met. It＇ s also the survival and development direction of hospital preparations in the future.