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肿瘤恶病质治疗药物的基础和临床研究进展 被引量:1

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摘要 目的:综述目前肿瘤恶病质治疗药物的基础和临床研究,为临床药物治疗提供依据,为药物研发提供参考。方法:检索近年来肿瘤恶病质治疗药物的临床试验和基础研究相关文献,对临床治疗药物和在研药物进行综述。结果与结论:肿瘤恶病质的治疗主要针对体质量减轻。食欲刺激药孕激素是因为水潴留增加体质量,并不能有效改善肌肉萎缩;筛选具有对抗肌肉萎缩的药物,才能从根本上给肿瘤恶病质患者带来福音。中医药在肿瘤恶病质治疗中发挥了重要作用,但临床疗效评价标准的缺乏限制了其推广应用,建立恶病质分期治疗标准有助于中医药在肿瘤恶病质治疗中作用的发挥,也有助于恶病质治疗药物的研发。
出处 《中国药房》 CAS CSCD 2014年第14期1320-1323,共4页 China Pharmacy
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  • 1Nicolini A,Ferrari P,Masoni MC,et al.Malnutrition,anorexia and cachexia in cancer patients:A mini-review on pathogenesis and treatment[J].Biomed Pharmacother,2013,67(8):807-817.
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