氟比洛芬酯用于胰十二指肠手术超前镇痛的效果观察被引量：2

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摘要丙泊酚复合瑞芬太尼因镇痛强、苏醒快,而广泛用于普通腹部外科手术.单大剂量或长时间应用会诱发疼痛加剧或痛觉异常,停止输注后患者可出现剧烈疼痛甚至痛觉过敏,导致术后镇痛药需求增加,对患者术后安全和恢复不利[1].氟比洛芬酯注射液是一种以脂微球为载体的具有靶向镇痛作用的新型非甾类抗炎镇痛药,临床镇痛效果良好[2].笔者选择所在医院40例胰十二指肠手术患者于手术结束前静脉滴注氟比洛芬酯,观察其镇痛效果,现报告如下.

作者闫文正李萍王锦波

机构地区解放军

出处《实用医药杂志》 2014年第3期223-224,共2页 Practical Journal of Medicine & Pharmacy

关键词氟比洛芬酯胰十二指肠手术超前镇痛

分类号 R614 [医药卫生—麻醉学] R656.6 [医药卫生—外科学]

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参考文献4

1王庚,吴新民.瑞芬太尼复合麻醉患者术后急性阿片类药物耐受的发生[J].中华麻醉学杂志,2007,27(5):389-392. 被引量：88
2孙振涛,韩雪萍,苗丽君,张卫,腾如阳,刘献志.凯纷用于颅脑手术术后镇痛效果观察及其对凝血功能的影响[J].山东医药,2007,47(15):34-35. 被引量：14
3杭黎华,邵东华,王洪,周蓓,黄霞萍,顾月萍.氯胺酮抑制瑞芬太尼致患者术后痛觉过敏的量效关系[J].中华麻醉学杂志,2009,29(9):780-781. 被引量：8
4邹志清,李立,吴周全.静脉低剂量氯胺酮超前镇痛对腹腔镜胆囊切除术后苏醒和疼痛的影响[J].临床麻醉学杂志,2009,25(5):387-388. 被引量：18

二级参考文献31

1蒋宗滨.非甾体抗炎药不良反应的临床研究[J].中国疼痛医学杂志,2006,12(4):241-243. 被引量：36
2Shir Y,Raja SN,Frank SM.The effect of epidural versus general anesthesia on postoperative pain and analgesic requirements in patients undergoing radical prostatectomy.Anethesiology,1994,80:49-56.
3Woolf CJ,Chong MS.Preemptive analgesia treating postoperative pain by preventing the establishment of central sensitization.Anesth Analg,1993,77:362-367.
4Katz J,McCartney CJ.Current status of preemptive analgesia.Curr Opin Anaesthesiol,2002,15:435-441.
5Barash PG,Cullen BF,Stoelting RK.Clinical Anesthesia.5th ed.Philadelphia:Lippincott Williams & Wilkins,2005:277-283.
6Guntz E, Talla G, Roman A, et al. Opioid-induced hyperalgesia. Eur J Anaesthesiol, 2007, 24: 205-207.
7Kitamura T, Kawamura G, Iwanaga S, et al. Effects of preoperative ketamine on postoperative pain in patients undergoing laparotomy. Masui, 2008,57 : 963-967.
8Joly V, Richebe P, Guignard B, et al. Remifentanil-induced postoperative hyperalgesia and its prevention with small-dose ketamine: Anesthesiology, 2005, 103: 147-155.
9Himmelseher S, Ziegler-Pithamitsis D, Argiriadou H, et al. Small-dose S ( + )-ketamine reduces postoperative pain when applied with ropivacaine in epidural anesthesia for total knee arthroplasty. Anesth Analg, 2001, 92: 1290-1295.
10Verburg KM,Maziasz TJ,Weiner E,et al.Cox-2-specific inhibitors:definition of a new therapeutic concept[J].Am J Ther,2001,8(1):49-64.