非高密度脂蛋白胆固醇及其与高密度脂蛋白胆固醇比值与2型糖尿病早期肾病的相关性研究

Association of non-HDL-cholesterol and non-HDL-cholesterol-to-HDL-cholesterol ratio with early diabetic nephropathy in patients with type 2 diabetes mellitus

探讨非高密度脂蛋白胆固醇（non-HDL-C）及其与高密度脂蛋白胆固醇比值（non-HDL-C／HDL-C）与2型糖尿病早期肾病的关系。发现non-HDL-C及non-HDL-C／HDL-C与微量白蛋白尿呈正相关（P〈0．05或P〈0．01），non-HDL-C／HDL-C是2型糖尿病早期肾病发生的独立危险因素。

The association of non-HDL-cholesterol and non-HDL-C-to-HDL-cholesterol ratio （ non-HDL-C- to-HDL-C ratio） with early diabetic nephropathy in patients with type 2 diabetes mellitus was investigated. Non-HDL- C and non-HDL-C-to-HDL-C ratio were positively related with microalbuminuria （ P〈0.05 or P〈0.01 ）. Non-HDL-C- to-HDL-C ratio is an independent risk factor of early diabetic nephropathy in patients with type 2 diabetes mellitus.