摘要
背景与目的不同组织学类型肺癌患者发病特点、预后情况不同。本研究旨在分析不同组织学类型肺癌患者发病情况、发病趋势、生存期及其影响因素,为病因学研究和临床防治提供参考依据。方法以2002年-2009年上海市浦东新区居民为研究对象,利用年度变化百分比进行肺癌发病趋势分析。通过寿命表法计算生存率,以Log-rank检验生存曲线差异。结果该地区同期肺癌男女标化发病率分别为52.28/10万和18.86/10万,明确组织学分型的肺癌患者中位生存期为410.72天。腺癌发病率最高并成上升趋势(P<0.05)。小细胞癌生存情况最差。原南汇地区男性鳞癌生存情况较好。结论不同组织学类型肺癌发病趋势和生存期并不相同,性别、年龄、居住地对不同组织学类型肺癌患者生存期有影响。
Background and objective Different histologies of lung cancer vary in occurrence and prognosis. This study aims to analyze the incidence and occurrence trend of lung cancer and investigate the survival rate and its influential factors among lung cancer patients with different histologies. Methods Permanent residents were recruited between 2002 and 2009 in Pudong New Area (former Nanhui Area and former Pudong Area), Shanghai, China. Annual percent changes were estimated by a linear regression of the logarithm on the incidence rates for eight years. Survival rates were calculated and com- pared by using life-table analysis and Log-rank test, respectively. Results The standardized incidence rates of lung cancer were 52.28 and 18.86 per 100,000 in males and females, respectively. The median survival time was 410.72 days for specific classified lung cancer. The incidence rates of adenocarcinoma ranked the highest and showed an upward tendency (P〈0.05). Patients with small cell lung cancer showed the worst survival condition. The survival condition in males with squamous cell lung cancer living in former Nanhui Area was better compared with those living in former Pudong Area. Conclusion Lung cancers with different histologies demonstrated different occurrence trends and survival rates. Gender, age, and living area influence the survival rates of lung cancer with different histologies.
出处
《中国肺癌杂志》
CAS
北大核心
2014年第3期203-208,共6页
Chinese Journal of Lung Cancer
基金
浦东新区卫生系统重点专科建设(No.PWZz2013-15)项目资助~~
关键词
肺肿瘤
生存分析
发病趋势
影响因素
Lung neoplasms
Survival analysis
Incidence trend
Influential factors