期刊文献+

微生态制剂治疗炎症性肠病 被引量:7

原文传递
导出
摘要 人体内和体表有数以万亿的微生物寄居,人体内细胞约有90%为微生物细胞,其余约10%为人体细胞,因此从某种意义上说人体是由诸多物种组成的复合体.微生态(microbiota)概念的提出打破了以往某种致病菌直接导致疾病的认识模式,越来越多的证据显示,肠道微生物在许多疾病的发生发展中起重要作用.
出处 《中华医学杂志》 CAS CSCD 北大核心 2014年第8期627-629,共3页 National Medical Journal of China
  • 相关文献

参考文献18

  • 1Le Chatelier E, Nielsen T, Qin J, et al. Richness of human gut microbiome correlates with metabolicmarkers [ J ]. Nature, 2013, 500:541-546.
  • 2Human Microbiome Project Consortium. Structure, function and diversity of the healthy human microbiome [ J ]. Nature ,2012 ,486 : 207 -214.
  • 3Gaboriau-Routhiau V, Rakotobe S, Lecuyer E, et al. The key role of segmented filamentous bacteria in the coordinated maturation of gut helper T cell responses [ J ]. Immunity 2009,31:677-689.
  • 4Sokol H, Pigneur B, Watterlot L, et al. Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients [ J ]. Proc Natl Acad Sci U S A,2008,105,16731-16736.
  • 5Cadwell K, Patel KK, Maloney NS, et al. Virus-plus-susceptibility gene interaction determines Crohn' s disease gene Atgl6L1 phenotypes in intestine[ J]. Cell ,2010,141 : 1135-1145.
  • 6Steed H, Maefarlane GT, Blackett KL, et al. Clinical triM: the microbiological and immunological effects of synbiotic consumption a randomized double-blind placebo-controlled study in active Crohn' s disease [ J ] . Aliment Pharmacol Ther, 2010,32:872-883.
  • 7Schultz M, Timmer A, Herfarth HH, et al. Lactobacillus GG in inducing and maintaining remission of Crohn's disease [ J ]. BMC Gastroenterol, 2004,4 : 5.
  • 8Guslandi M, Mezzi G, Sorghi M, et al. Saccharomyces boulardii in maintenance treatment of Crohn's disease [ J ]. Dig Dis Sci, 2000, 45 : 1462-1464.
  • 9Bousvaros A, Guandalini S, Baldassano RN, et al. A randomized, double-blind trial of Lactobacillus GG versus placebo in addition to standard maintenance therapy for children with Crohn's disease [ J]. Inflamm Bowel Dis,2005,11:833-839.
  • 10Marteau P, Lemann M, Seksik P, et al. Ineffectiveness of Lactobacillus johnsonii LA1 for prophylaxis of postoperative recurrence in Crohn' s disease: a randomised, double blind, placebo controlled GETAID trim [ J ]. Gut,2006,55 : 842-847.

二级参考文献11

  • 1PodolskyDK. Inflammatory bowel disease [J ] . N Engl J Med.2002,347(6):417.
  • 2RoglerG. Update in inflammatory bowel disease pathogenesis[ J ] .Curr Opin Gastroenterol, 2004 ; 20 : 311.
  • 3Martinez-MedinaM, Aldeguer X, Gonzalez-Huix F, et al. Abnor-mal microbiota composition in the ileocolonic mucosa of Crohn ’ sdisease patients as revealed by polymerase chain reaction-denatu-ring gradient gel electrophoresis[J"] . Inflamm Bowel Dis, 2006 ,1 2(12):1136.
  • 4MazmanianSK,Round JL,Ksaper DL. A microbial symbiosis factor prevents intestinal inflammatory disease[J] . Nature . 2008,453(7195):620.
  • 5JiaW, Li H ,Zhao L,et al. Gut microbiota : a potential new territo-ry for drug targeting[J] . Nat Rev Drug Discov, 2008,7(2) :123.
  • 6CummingsJH,Macfarlane (tT, Macfarlane S. Intestinal bacteriaand ulcerative colitis[J] . Curr Issues Intest Microbiol 2003,4:9.
  • 7MadsenKL,Doyle JS,Tavernini MM,et al. Antibiotic therapy altenuates colitis in interleukin 10 gene-deficient mice[J] . Gastroen-terology, 2000,118( 6) : 1094.
  • 8KruisW, Fric P, Pokrotnieks J, Lukas M, et al. Maintaining remission of ulcerative colitis with the probiotic Escherichia coliNissle 1917 is as effective as with standard mesalazine[J"J. Gut,2004,53:1617.
  • 9Fuller R. Probiotics in man and animals [J ] . J Appl Bacteriol,1989;66:365.
  • 10VanderpoolC, Yan F,Polk DB. Mechanisms of probiotic action:Implications for therapeutic applications in Inflammatory boweldiseases[J] . Inflamm Bowel Dis,2008,14(11) ; 1585.

共引文献22

同被引文献79

  • 1白爱平,欧阳钦.益生菌治疗炎症性肠病的机制[J].胃肠病学,2005,10(4):240-242. 被引量:33
  • 2崔静,刘占举,唐芙爱.炎症性肠病患者血清肿瘤坏死因子和白介素8检测[J].郑州大学学报(医学版),2006,41(5):825-827. 被引量:20
  • 3王丽红,李慧华.微生态制剂美常安治疗溃疡性结肠炎的临床观察.中国药物经济学,2014,7:236-237.
  • 4Brenner DM, Moeller MJ, Chey WD, Schoenfeld PS. The utility of probiotics in the treatment of ir- ritable bowel syndrome: a systematic review. Am ]Gastroenterol ,2009, 104: 1033-1049, quiz 1050 [PMID: 19277023 DOI: 10.1038/ajg.2009.25].
  • 5Pimentel M, Lembo A, Chey WD, Zakko S, Ringel Y, Yu J, Mareya SM, Shaw AL, Bortey E, Forbes WP. Rifaximin therapy for patients with irritable bowel syndrome without constipation. N Engl J Med ,2011,364:22-32 [PMID: 21208106 DOI: 10.1056/NEJ- Moa1004409].
  • 6中国炎症性肠病诊断治疗规范的共识意见[J].中华内科杂志,2008,47(1):73-79. 被引量:379
  • 7Martine Z, Medina M, Aldeguer X, et al. Abnormal microbio- ta composition in the ileocolonic mucosa of Crohn's disease pa- tients as revealed by polymerase chain reaction denaturing gra-dient gel electrophoresis[J].Inflamm Bowel Dis, 2006, 12 (12) : 1136-1146.
  • 8Fuller R. Probiotics in man and animals[J]. J Bacteriol, 1989, 66(5) : 365-378.
  • 9Vanderpool C, Yan F, Polk DB. Mechanisms of probiotic action: Implications for therapeutic applications in inflammatory bowel dis- ease[J]. Inflamm Bowel Dis, 2008, 14(11): 1585.
  • 10Kruis W, Fric P, Pokrotnieks J, et al. Maintaining remission of ulcerative colitis with the probiotic Escherichia coli Nissle 1917 is as effective as with standard mesalazine[J]. Gut, 2004, 53(11): 1617-1623.

引证文献7

二级引证文献105

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部