不同世代改良型路南奶山羊血液免疫学参数的比较研究

THE COMPARATIVE STUDY ON IMMUNE VALUATION OF BLOOD IN LUNAN MILCH GOAT IMPROVEMENT OF DIFFERENT GENERATIONS

本文测定了“改良型路南奶山羊”的亲本及改良不同世代 (F1,F2 ,F3,F4 )母羊的外周血T淋巴细胞转化率、ANAE阳性率、B淋巴细胞ZYC花环率、红细胞IC花环率、C3b花环率以及血清γ -球蛋白等免疫学参数 ,比较研究其随着世代增递的变异情况。结果表明 :从亲代到F4代随着改良世代的递增 ,T淋巴细胞转化率、ANAE阳性率、红细胞C3b花环率和IC花环率和血清γ -球蛋白含量均呈F1>F2 >P >F3>F4变化 ,ZYC花环率呈F1>P >F2 >F3>F4变化。回归分析的结果表明 :从亲代到改良四代 ,上述各项免疫学参数均呈显著负相关 ,趋势线为下降趋势。即随着世代的递增有逐代递减的趋势。结果提示 :用西农莎能羊改良路南圭山羊 ,其改良一代和二代的上述各项血液免疫学参数均略高于路南圭山羊 ,以后随着世代的递增有逐代递减的趋势。预示着随着世代的递增 ,改良型路南奶山羊的体质状况 ,免疫功能和抗病能力可能会出现下降趋势。

The six immune parameters,such as LTf(lymphocyte transformation),ANAE positive cells,ZYC rosettes on B cells,C3b and IC rosettes on red cells and serum γ-globulin were determined in the blood of Lunan milch goat improvement of different generations.The results showed that:LTf,ANAE,C3b,IC,and γ-globulin were shown as F2>F1>P>F4>F3,the ZYC was shown as F1>P>F2>F3>F4.From P(parental generation)to F4(the fourth improvement generation),the six immune parameters appeared to decrease with increase of generations.