术中放射治疗在膀胱癌治疗中的应用分析

Intraoperative radiotherapy in treatment of bladder cancer

目的探讨术中放射治疗膀胱癌的临床疗效。方法选择2002—2010年收治的62例膀胱癌患者,随机分成两组,其中治疗组32例,对照组30例,治疗组患者手术中给予放射治疗,对照组患者给予单纯手术治疗,比较两组患者总生存率、无复发生存率、无远处转移生存率以及住院时间。结果两组患者随访均超过3年,随访率均为100.00%,两组间总生存率、无复发生存率及无远处转移生存率均有统计学差异(均P<0.05),住院时间无统计学差异(P>0.05)。结论术中放射治疗膀胱癌疗效显著,可有效提高无复发生存率、无远处转移生存率及总生存率,且不增加术后住院时间,值得在临床上推广使用。

Objective To evaluate the clinical efficacy of intraoperative radiotherapy for bladder cancer. Methods Sixty two patients with bladder cancer admitted in Zhuji People＆#39;s Hospital from 2002 to 2010 were randomly assigned to two groups：32 cases underwent tumor resection and intraoperative radiotherapy （study group） and 30 cases received tumor resection alone （control group） . The overal survival rate, relapse- free survival, metastasis- free survival and length of hospital stay were com-pared between two groups. Results The patients were fol owed up for〉3y with a fol ow- up rate of 100.00%. The overal sur-vival rate, relapse- free survival, and distant metastasis- free survival rate in study group were significantly longer than those in control group （P〈0.05）;however, there was no difference in length of hospital stay between two groups （P〉0.05）. Conclusion The intraoperative radiotherapy can effectively improve the overal survival, relapse- free survival and distant metastasis- free sur-vival for patients with bladder cancer.