摘要
目的研究新定义的真性左束支传导阻滞对慢性心力衰竭患者心脏再同步化治疗(CRT)的应答率是否提高。方法回顾性分析在兰州大学第一医院行CRT治疗患者的临床资料,分析术前心电图不同形态QRS波与预后的关系。结果 62例患者中,真性左束支传导阻滞组24例,假性左束支传导阻滞组16例和非左束支传导阻滞组22例,经(49.1±48.5)个月随访,CRT术后患者左室射血分数和NYHA心功能分级显著改善。术前心电图QRS波形态与CRT患者全因死亡和因心力衰竭再入院率无关。多变量回归分析表明真性左束支传导阻滞和年龄是CRT后发生超应答的强力预测因子。结论真性左束支传导阻滞是CRT术后发生超应答的强力预测因子。
Objective To verify if newly proposed criteria for true left budle branch （LBBB） identify patients with a better clinical and instrumental response to cardiac resynchronization therapy（CRT）. Methods We retrospectively en- rolled patients received a CRT device in First Hospital of Lanzhou University and analyse different forms of QRS wave in pre-operation electrocardiogram predictors prognosis. Results Sixty-two patients enrolled, 24 in true LBBB, 16 in false LBBB and 22 in no-LBBB. After （49.1±48.5 ） months＇ follow up, left ventricular ejection fraction and mean New York Heart class improved observably. There was no statistical difference in different forms of QRS wave in all-cause mortality and hospital admission with heart failure. Multivariate analysis showed that true LBBB and age were independent predictors of super response to CRT. Conclusion True LBBB morphology is related to a higher super-response rate in CRT pa- tients.
出处
《中国心脏起搏与心电生理杂志》
2014年第1期16-20,共5页
Chinese Journal of Cardiac Pacing and Electrophysiology
关键词
心血管病学
心脏再同步化治疗
心电图
心力衰竭
左束支传导阻滞
超应答
Cardiology
Cardiac resynchronization therapy
Electrocardiology
Heart failure
Left bundle branchblock
Super response
