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结节病诊断相关的生物学标记物研究进展 被引量:2

Progress of biological markers in sarcoidosis diagnosis
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摘要 结节病是一种原因不明的、以非干酪样坏死性上皮细胞肉芽肿为病理特征的系统性疾病,临床表现无特异性,其生物学标记物为近年研究热点。本文对结节病诊断相关的生物学标记物的研究进展作一综述,以期为进一步的相关研究提供参考。 Sarcoidosis is a multisystem inflamatory disease pathologically characterized by non- caseating necrotizing epithelial cell granuloma. Its etiology and pathogenesis remain unknown. And it is lack of specificity of clinical sympotoms. In recent years, its molecular biological markers have become research hotspots. Here we review the new researches on the molecular biological markers in sarcoidosis diagnosis, which might be helpful for further research.
作者 刘超 黄建安
出处 《国际呼吸杂志》 2014年第6期468-472,共5页 International Journal of Respiration
关键词 结节病 诊断 生物学标记物 Sarcoidosis Diagnosis Biological marker
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参考文献28

  • 1Iannuzzi MC, Rybicki BA, Teirstein AS. Sarcoidosis [J]. N Engl J Meal,2007,357:2153 -2165.
  • 2Kitaichi N, Kitamura M, Namba K, et al. Elevation of surfactant protein D, a pulmonary disease biomarker, in the sera of uveitis patients with sareoidosis [ J ]. Jpn J Ophthalmol, 2010,54 : 81-84.
  • 3Kucejko W, Chyczewska E, Naumnik W, et ai. Concentration of surfactant protein D,Clara cell protein CC-16 and IL-10 in bronchoalveolar lavage (BAL) in patients with sarcoidosis, hypersensivity pneumonitis and idiopathic pulmonary fibrosis [J]. Folio Histochem Cytobiol, 2009,47 : 225-230.
  • 4Bargagli E, Magi B, Olivieri C, et al. Analysis of serum amyloid A in sarcoidosis patientsEJ[J]. Respir Med, 2011,105 : 775- 780.
  • 5Chen ES, Song Z, Willett MH, et al. Serum amyloid A regulates granulomatous inflammation in sarcoidosis through Toll like receptor-2[J]. Am J Respir Crit Care Med, 2010, 181:360- 373.
  • 6Piotrowski WJ, Nawrocka-Kunecka A, Antczak A, et al. Metalloproteinases MMP-9, MMP-2 and their tissue inhibitors TIMP-1,TIMP-2 in peripheral transbronchial lung biopsies of patients with sarcoidosis [J]. Pol Arch Med Wewn, 2009,119 : 628-635.
  • 7周乐飞,姜莉,李振华,康健.特发性肺纤维化和结节病患者基质金属蛋白酶的变化及其临床意义[J].中华结核和呼吸杂志,2010,33(6):441-444. 被引量:10
  • 8Shimada A, Koga Y, et al. Reduced pulmonary function is associated with enhan inhibitor of metalloproteinase bronehoalv parenchym ted inflammation and lar lavage fluid of patients with tissue the lung sarcoidosis[J]. Kurume Med J ,2008,55:13- 17.
  • 9Miyoshi S, Hamada H, Kadowaki T, et al. Comparative evaluation of serum markers in pulmonary sarcoictosis[J]. Chest,2010,137 : 1391- 1397.
  • 10Honda K,Okada F,Ando Y,et al. Comparison of pulmonary thin section CT findings and serum KL 6 levels in patients with sarcoidosis[J]. Br J Radiol, 2011,84 : 229-235.

二级参考文献12

  • 1Rosas IO,Riehards TJ,Konishi K,et al.MMP1 and MMP7 as potential peripheral blood biomarkers in idiopathic pulmonary fibrosis.PLoS Med,2008,5:e93.
  • 2American Thoracic Society,European Respiratory Society.American Thoracic Society/European Respiratory Society International Muhidisciplinary Consensus Classification of the Idiopathic Interstitial Pneumonias.This joint statement of the American Thoracic Society (ATS),and the European Respiratory Society (ERS) was adopted by the ATS board of directors,June 2001 and by the EBS Executive Committee,June 2001.Am J Bespir Crit Care Med,2002,165:277-304.
  • 3Zuo F,Karninski N,Eugui E,et al.Cene expression analysis reveals matrilysin as a key regulator of pulmonary fibrosis in mice and humans.Prac Nail Acad Sci U S A,2002,99:6292-6297.
  • 4Selman M,Ruiz V,Cabrera S,et al.TIMP-1,-2,-3 and -4 in idiopathic pulmonary fibrosis.A prevailing nondegradative lung microenvironment? Am J Physioi Lung Cell Mol Physiol,2000,279:L562-L574.
  • 5Li Q,Park PW,Wilson CL,et al.Matrilysin shedding of syndecan-1 regulates chemokine mobilization and transepithelial efflux of neutrophils in acute lung injury.Cell,2002,111:635-646.
  • 6McGuire JK,Li Q,Parks WC.Matrilysin (matrix metalloproteinase-7) mediates E-cadhefin ectodomain shedding in injured lung epithelium Am J Pathol,2003,162:1831-1843.
  • 7Vuorinen K,Myll(a)rniemi M,Lammi L,et al.Elevated matrilysin levels in bronchoalveolar lavage fluid do not distinguish idiopathic pulmonary fibrosis from other interstitial lung diseases.APMIS,2007,115:969-975.
  • 8Cosgrove GP,Schwarz MI,Geraci MW,et al.Overexpression of matrix metalloproteinase-7 in pulmonary fibrosis.Chest,2002,121(3 Suppl):25S-26S.
  • 9Rosas IO,Ren P,Avila NA,et al.Early interstitial lung disease in familial pulmonary fibrosis.Am J Respir Crit Care Med,2007,176:698-705.
  • 10Steele MP,Speer MC,Loyd JE,et al.Clinical and pathologic features of familial interstitial pneumonia.Am J Respir Crit Care Med,2005,172:1146-1152.

共引文献9

同被引文献24

  • 1结节病诊断及治疗方案(第三次修订稿草案)[J].中华结核和呼吸杂志,1994,17(1):9-10. 被引量:149
  • 2施举红,许文兵,张竹花,刘鸿瑞,朱元珏,王京岚,肖毅,徐作军,蔡柏蔷.肺结节病46例病理及胸部CT特征[J].中华结核和呼吸杂志,2007,30(8):561-564. 被引量:17
  • 3Anonymous Statement on sarcoidosis. Joint Statement of the American Thoracic Society (ATS), the European Respiratory Society (ERS) and the World Association of Sarcoidosis and Other Granulomatous Disorders (WASOG) adopted by the ATS Board of Directors and by the ERS Executive Committee,February 1999 [J]. Am J RespirCrit Care Meal,1999,160(2) : 736-755. D10 : 10.1164/ajrccrn. 160.2. ats4-99.
  • 4Douglas JG, Middleton WG, Gaddie J, et al. Sarcoidosis: a disorder commoner in non-smokers? [J]. Thorax, 1986, 41 (10) :787-791. DIO: 10. l136/thx. 41.10. 787.
  • 5Domagala-Kulawik J, Urbankowski T, Safianowska A. S Fas in bronchoalveolar lavage fluid of patients with sarcoidosis in relation to cigarette smoking [J]. Hum Immunol, 2013, 74 (7) :858-860. DIO: 10. 1016/j. humimm. 2013.04. 015.
  • 6Osinska I, Wolosz D, Domagala-Kulawik J. Association between M1 and M2 macrophages in bronchoalveolar lavage fluid and tobacco smoking in patients with sarcoidosis[J]. PoI Arch Med Wewn, 2014, 124(7/8) :359-364.
  • 7Hattori T, Konno S, Shijubo N, et al. Increased prevalence of cigarette smoking in Japanese patients with sarcoidosis [J]. Respirology, 2013, 18 (7): 1152-1157. DIO: 10. llll/resp, 12153.
  • 8Taskar V, Couhas D. Exposures and idiopathic lung disease [J]. Semin Respir Crit Care Med, 2008,29(6) : 670-679. DIO : 10. 1055/s-0028-1101277.
  • 9No authors listed. Design of a case control etiologic study of sarcoidosis (ACCESS). ACCESS Research Group [J]. J Clin Epidemiol, 1999, 52 (12) : 1173-1186. DOI: http://dx, doi. org/I0.I016/S0895-4356(99)00142-0.
  • 10Sharma OP. Cutaneous sarcoidosis: clinical features and management[J]. Chest, 1972,61 (4) : 320-325. DIO : 10. 1378/ chest. 61.4. 320.

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