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表皮极性及极性蛋白在银屑病中研究进展 被引量：5

The Epidermal Polarity and The Polarity Protein in Psoriasis Research
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摘要 表皮极性的建立是角质形成细胞增殖、分化的重要环节,其丧失和紊乱是一些病理生理过程产生的生物学基础。银屑病是一种常见的由遗传背景控制的、慢性炎症性、免疫性、良性增殖性疾病,具有病程长、易反复等特点,这些与其发病机制复杂关系密切。本文综述了与银屑病相关的极性蛋白研究进展,目前的研究可能会引起银屑病方面的突破。 The epidermal polarity establishment is crucial for proliferation and differentiation of keratinocyte.Sometimes disruption of epidermal polarity is the base of pathophysiologic process.Psoriasis is a frequent,genetic,chronic inflammatory,benign proliferative disease,characterized by long course,easily recurrence,which is related with unsolved pathogenesis.This paper presents the advances in the research of the polarity protein which is associated with psoriasis.The current research may bring a bright future in the psoriasis.
作者 赵丽阳 张艳飞 郑瑞
机构地区 山西医科大学第一医院
出处 《中国医学创新》 CAS 2014年第6期143-146,共4页 Medical Innovation of China
关键词 极性蛋白 紧密连接 银屑病 The polarity protein Tight junction Psoriasis
分类号 R758.63 [医药卫生—皮肤病学与性病学]
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参考文献28

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二级参考文献14

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中国医学创新
2014年 第6期

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