早期肠道内营养支持对重度烧伤病人预后的影响

Prognosis effect of early enteral nutrition support in patients with severe burn

目的探讨早期肠道内营养支持对重度烧伤患者康复的影响。方法大面积烧伤患者80例,随机分为观察组与对照组,各40例,观察组采用早期肠道内营养支持,对照组采用肠道外营养支持,对比2组患者创面恢复及营养状况。结果观察组患者正氮平衡恢复、创面愈合时间均较对照组显著缩短,组间比较差异有统计学意义(P<0.05);观察组血清内毒素较对照组降低显著,且脓毒症发病率及营养状况均优于对照组,组间比较差异有统计学意义(P<0.05)。结论早期肠道内营养支持可有效降低烧伤导致的高代谢反应,降低患者血清内毒素,减少感染性并发症发生,改善患者营养状况,利于患者恢复。

Objective To study the effect of early enteral nutrition support on rehabilitation of patients with severe bum. Methods 80 patients with large area bum were randomly divided into observation group and control group. The early enter- al nutrition support was given in observation group. The intestines nutrition support was given in control group. Patients＇ wound recovery and nutritional status were compared between the two groups. Results Positive nitrogen balance recovery time and wound healing time of observation group were more significantly shortened than those of control group. There was statistically significant difference between groups （ P 〈 0.05）. The serum endotoxin in observation group was reduced signifi- candy. The incidence of sepsis and nutritional status were superior to those of control group. There was statistically significant difference between groups （ P 〈 0.05）. Conclusion Early enteral nutrition support in bum treatment can effectively reduce the high metabolic reactions, serum endotoxin and infectious complications of patients, and improve the nutritional status to facilitate the patients＇ recovery.