血液病合并感染及中西医结合疗效回顾性研究

Medical data analysis and observation on therapeutic effect of combine traditional Chinese with Western Medicine of hematological diseases complicated with infection

[主要目的]分析血液科患者感染临床特征以及中西医结合治疗情况。[资料来源]选取辽宁中医药大学附属医院血液科2011年6月～2013年6月住院血液病合并感染463例患者。发放血液病合并感染多因素调查表。[选择文献量及依据]①研究类型：临床观察。②研究对象：入院后确诊为血液病合并感染；同一患者反复入院时重复纳入。③诊断分型：血液病诊断标准参照《血液病诊断及疗效标准》；感染诊断标准参照《医院感染诊断标准》。④评价指标：血常规、病原学检测结果。[数据提炼规则及应用方法]制定“血液科合并感染特点调查表”。查阅血液科合并感染患者病历及化验单．填写“血液科合并感染特点调查表”。使用Microsoft Excel2013建立数据库．分析感染与原发病、感染部位。[数据综合得出结果与结论]①各类恶性血液病患者感染比例最高：②感染部位以呼吸道感染比例最高：③阳性病原茵检测中以大肠埃希菌感染比例最高；④患者感染因素中以中性粒细胞计数在0．5×10^9／L以下感染率最高．⑤中西医结合抗炎疗效优于单纯抗生素抗炎。[未来展望]血液病患者易发生感染，未来应加强防范措施．降低感染发病率：治疗过程中应提高病原学检测水平．应用敏感抗生素：中西医联合抗炎。

[ Objectives ] To investigate the clinical characteristics and combined treatment of traditional Chinese with Western Medicine in the patients with hematological diseases complicated with infection. [ Materials source ] The medical records of 463 patients with hematological diseases complicated with infection in June, 2011 - June, 2013 in First Affiliated Hospital of Liaoning University of Traditional Chinese Medicine. [ Quantities and criteria ] （1）Research type ： clinical observation.（2）Research objects ： After admission diagnosis of hematological diseases complicated with infection; Repeated the same patients admitted to hospital repeat into.（3）Diagnostic classification： Hematological diseases standard reference Standard of diagnosis and curative effect of blood disease ; Infection standard reference The standard of diagnosis of hospital infection.（4）Evaluation indicator： Assay index of blood RT and nosetiology. [ Data extraction rules and Methods of application ] （1）he highest proportion of patients with infection is the patients with malignant hematological disease.（2）The highest proportion of infection site is respiratory tract infection.（3）Fhe highest proportion of pathogenic bacteria is the Escherichia coli.（4）The highest proportion of infection factor is Nentrophil count below 0.5×10^9//L.（5）Therapentie effect of combine traditional Chinese and Western Medicine is superior to therapeutic effect of mere antibiotics. [ Future prospect ] Patients with hematologic disease are easily to be infected, therefore, they need strengthen preventive measures, and reduce the morbidity of infection; improve the level of pathogen detection, application of sensitive antibiotic ; anti-inflammatory therapy by combined treatment of traditional Chinese and western Medicine.