摘要
目的观察合并甲状腺功能亢进的2型糖尿病患者的临床指标,探讨甲状腺功能亢进对2型糖尿病患者代谢指标,骨密度及糖尿肾病的影响。方法对54例合并甲状腺功能亢进的2型糖尿病患者与104例甲状腺功能正常的2型糖尿病患者进行回顾性对照研究。结果合并甲状腺功能亢进的2型糖尿病患者与甲状腺功能正常的2型糖尿病患者相比:TC、LDL-C、左前臂骨密度、左髋骨骨密度、舒张压及体重指数均降低,eGFR升高,FBG、HbA1c、TG、HDL-C、收缩压及尿白蛋白/肌酐上均无差异。结论甲亢降低2型糖尿病患者TC、LDL-C、舒张压及体重指数,升高eGFR,合并甲亢的2型糖尿病应积极控制血糖,防止骨质疏松。
Objective To observe the clinical characteristics merged hyperthyroidism of patients with type 2 diabetes in order to investigate hyperthyroidism effects on patients with type 2 diabetes in metabolic marker,bone mineral density and diabetic nephropathy. Methods Fifty-four cases of type 2 diabetes with hyperthyroidism and 104 cases of euthyroid type 2 diabetes were retrospectively studied. Results Compared to the euthyroid diabetics,the type 2 diabetics combined with hyperthyroidism has less total cholesterol,low density lipoprotein cholesterol,left forearm bone mineral density,left hip bone mineral density,diastolic pressure and body mass index and better estimated glomerular filtration rate. Fasting glucose,glycosylated hemoglobin A1c,triglycerides,high density lipoprotein cholesterol, systolic pressure and urinary albumin creatinine ratio had no significant differences. Conclusions Hyperthyroidism patients with type 2 diabetes have decreased TC,LDL-C,diastolic blood pressure and body mass index and increase eGFR. Type 2 diabetes mellitus with hyperthyroidism patients should actively control blood sugar to prevent osteoporosis.
出处
《安徽医药》
CAS
2014年第2期267-269,共3页
Anhui Medical and Pharmaceutical Journal
