红细胞分布宽度与急性脑出血患者预后的关系

Relationship of RDW with the prognosis in acute cerebral hemorrhage patients

目的探讨红细胞分布宽度(RDW)与急性脑出血发生及预后的关系,讨论其潜在作用机制。方法回顾分析2009—2011年在该院神经内科住院治疗的150例急性脑出血患者及160例非急性脑出血患者,采集其一般情况、实验室检测指标及预后情况,分析RDW与急性脑出血预后的关系。结果 (1)急性脑出血患者合并高血压病者明显多于非脑出血患者(65.33%vs 43.08%,P<0.01);(2)对比非脑出血患者,急性脑出血患者RDW水平更高(13.50±0.71)%vs(12.79±0.58)%,P<0.01);(3)急性脑出血患者中,RDW越高,反复发生脑出血的人数及住院病死率也更高。结论 RDW与急性脑出血患者预后明显相关,急性脑出血患者的住院病死率随RDW水平的增加而升高,预示着RDW可能是判断急性脑出血患者预后的较强预测因子。

Objective To measure the relationship between RDW and acute cerebral hemorrhage as well as prognosis. Methods Data of 150 patients with acute cerebral hemorrhage and 160 patients with non-acute cerebral hemorrhage,including physical examination,laboratory tests and prognosis were retrospectively analyzed. Results More hypertension occurred in acute cerebral hemorrhage patients than non-acute cerebral hemorrhage patients（ P ＆lt; 0. 01）. Compared with the non-acute cerebral hemorrhage patients,the RDW was significantly higher in acute cerebral hemorrhage patients（ P ＆lt; 0. 01）. The increasing level of RDW contributed to the repeated occur reuce of cerebral hemorrhage and the increasing in-hospital mortality. Conclusions The relationship between the level of RDW and the prognosis of acute cerebral hemorrhage patients is significantly manifested. The increasing level of RDW contributed to the increasing in-hospital mortality. RDW is a widely-available test which is a strong predictor of prognosis of the acute cerebral hemorrhage patients.