AU680和AU400两种型号全自动生化分析仪测量氨基转移酶可比性的分析

Comparative analysis on two models of AU680 and AU400 fully automatic biochemical analyzer for measuring transaminase

目的分析AU680和AU400两种型号全自动生化分析仪测量谷丙氨酸转移酶(ALT)和天门冬氨酸转移酶(AST)的可比性。方法依据美国临床实验室改进修正法规88(CLIA′88)的要求,随机抽取55份患者样本,分别在AU680和AU400两种型号生化分析仪测量ALT和AST,用统计学方法分析计算其回归线性公式、相关系数及偏倚等。结果两种型号的生化分析仪ALT的测定结果其相关线性公式为Y=0.915 66 X+0.051 00,r=0.999 79;AST的测定结果其相关线性公式为Y=0.830 39 X+1.324 57,r=0.999 96。结论两种型号的生化分析仪相关性很好,测量结果比对校正后,可以同时为临床提供结果。

Objective To analysis the comparability of two models of AU680 and AU400 fully automatic biochemical analyzer for measuring alanine aminotranferase （ALT） and aspartate aminotransferase （AST）. Methods According to the requirement of the Clinical Laboratory Improvement Amendments Regulations 88 （ CLIA＇88）, 55 samples form the patients were randomly extrac- ted and detected AI.T and AST by the two models of AU680 and AU400 biochemistry analyzer respectively. The statistical method was adopted to analyze and calculate the linear regression equation,correlation coefficient and bias and so on. Results For the ALT results detected by the two models of biochemical analyzer, the linear equation was Y= 0. 915 66X＋ 0.051 00, the correlation coeffi-cient（r） =0. 99979 ;for AST measurement results,the linear equation was Y=0. 830 39X＋1. 324 57,r=0. 999 96. Conclusion The two models of biochemical analyzer have very good correlation, after comparison and correction, the measured results can simultane-ously provide the detection results for clinic.