子痫前期患者心率变异性与左室Tei指数研究

Comprehensive Study of Tei Index of Heart Rate Variability in Patients with Syndrome of Preeclampsia and Gestational Hypertension Left Ventricular

目的:研究子痫前期(preeclampsia}患者的心率变异性(HRV)与左室Tei指数的改变。方法:应用12通道动态心电图及超声心动图对102例子痫前期患者(实验组)与100例健康孕妇(对照组)的HRV时域指标及左室Tei指数进行对比分析。HRV时域指标:24小时平均窦性R-R间期的标准差(SDNN)相邻窦性R-R间期差值的均方根(rMSSD)。窦性相邻R-R间期差值>50ms的百分比(PNN50)。24小时每5min正常R-R间期平均值的标准差(SDANN);结果:子痫前期患者的SDNN、SDANN、rMSSD、PNN50与左室Tei指数较对照组差异有统计学意义(P<0.05)。结论:子痫前期患者心脏自主神经调控功能紊乱,迷走神经活性降低,交感神经活性增强,心功能降低。

Objective：Study of heart rate variability in patients with pre-eclampsia （HRV） and left ventricular Tei index change. Methods：By comparative study on HRV time-domain index and left ventricular Tei index through 12-channel dynamic electrocardiogram and ultrasonic heartbeat graph from 102 patients with preeclampsia （treatment group） and 100 healthy pregnant women （control group）. HRV time-domain indices：mean Sinus R-R interval standard deviation （SDNN） of adjacent sinus R-R interval difference of root mean square （rMSSD）. Sinus adjacent R-R interval difference 〉 50ms percentage （PNN50）. Every 5min normal R-R interval average value and standard deviation （SDANN）.Results：Preeclampsia patients with SPNN, SPANN, rMSSD, left ventricular Tei index than the control subjects difference was statistically significant （ P〈0.05 ）.Conclusion：The preeclampsia patients＆#39; cardiac autonomic regulation dysfunction, reduced vagal activity, enhanced sympathetic nervous activity,Cardiac function decrease.