急性病毒性心肌炎48例临床治疗效果观察

Clinical Therapeutic Effect Observation of 48 Cases of Acute Viral Myocarditis

目的:探讨急性病毒性心肌炎的临床诊断、治疗方法及治疗效果。方法:将我院收治的48例急性病毒性心肌炎患者,随机分为对照组和观察组。对照组采用常规对症支持治疗。观察组采用黄芪联合辅酶Q10治疗。比较两组治疗效果,治疗前后心电图改善情况,治疗前后CK-MB、CRP、CTnⅠ改善情况,治疗过程中不良反应发生情况。结果:观察组总有效率显著高于对照组,差异有统计学意义(P<0.05)。观察组治疗后各种心电图异常表现改善情况显著优于对照组,差异有统计学意义(P<0.05)。观察组治疗后CKMB、CRP、CTnⅠ改善情况显著优于对照组,差异有统计学意义(P<0.05)。观察组与对照组不良反应发生率经统计学分析,差异无显著性(P>0.05)。结论:在对症支持治疗的基础上加用黄芪+辅酶Q治疗,疗效优于常规对症支持治疗,治疗后心电图改善显著,各指标改善显著,不良反应少,值得临床推广应用。

Objective：To study the clinical diagnosis and treatment of acute viral myocarditis and the effect of treatment. Methods：48 cases of acute viral myocarditis patients of our hospital,were randomly divided into control group and observation group. Control group.Observation group treated with astragalus membranaceus combined coenzyme Q10.Compare two groups of curative effect,electrocardiogram （ecg） before and after treatment,before and after the treatment of CK-MB,CRP,CTn Ⅰ improvement,adverse reactions occurred in the process of treatment.Results：The observation group total effective rate was significantly higher than that of control group,the difference was statistically significant （P〈0.05）.Observation group after treatment all kinds of abnormal ecg performance improvement was significantly better than control group,the difference was statistically significant （P〈0.05）.Observation group after treatment CK-MB,CRP,CTnⅠimprovement significantly better than control group,the difference was statistically significant （P〈0.05）. Observation group and control group in incidence of adverse reactions after statistics analysis,there was no significant difference （P〉0.05）. Conclusion：In symptomatic support therapy on the basis of the treatment with astragalus root＋coenzyme Q,curative effect is superior to the conventional support treatment,electrocardiogram improved significantly after treatment,the index improved significantly,less adverse reactions,worthy of clinical popularization and application.