凝血功能和血小板检测在肾病综合征患者中的临床应用

Clinical Application of Coagulation and Platelets in Nephritic Syndrome Patients

目的：探讨凝血功能与血小板检测指标在肾病综合征患者中的临床应用价值。方法：选取我院2010年1月-2011年12月间60例肾病综合征患者为研究组，选取同期到我院健康检查的60名健康者为对照组，分别对两组的凝血功能和血小板指标进行测定。结果：研究组的APTT和FIB指标的数据与对照组的APTT和FIB指标比较具有明显的差异（P〈0.05），统计学有意义；研究组和对照组的PT和TT指标值比较无明显的差异（P〉0.05），统计学无意义。研究组的PLT和PCT以及MPV指标值与对照组的PLT和PCT以及MPV指标值比较近具有明显的差异（P〈0.05），统计学有意义；而研究组和对照组的PDW值比较无明显的差异（P〉0.05），统计学无意义。结论：肾病综合征患者均存在有不同程度的高凝状态，临床中加强凝血功能与血小板指标进行测定能够有效的对肾病综合征患者病情进行分析，并对血栓的形成诊断和临床治疗以及预后均具有较大的应用价值。

Objective：To investigate the coagulation and platelet indexes clinical value in patients with nephritic syndrome. Methods：In our hospital from January 2010 to December 2011,60 patients with nephritic syndrome patients for the study group,select the same period in 60 healthy subjects to our hospital health checks for the control group,respectively,of the two groups of coagulation and platelet the indicators were measured.Results：Study Group APTT and FIB indicators,data and control group APTT and FIB indicator of significant differences （P〈0.05）,statistically meaningful;study group and control group PT and TT index value,no significant difference （P〉0.05）,statistically meaningless.PLT and PCT,and MPV index value compared with the control group of the study group PLT and PCT and MPV index value of more recent significant differences （P〈0.05）,statistically meaningful;PDW value of the study group and the control group showed no significant difference （P〉0.05）,statistically meaningless.Conclusion：Patients with nephritic syndrome have varying degrees of hypercoagulable state,to enhance coagulation and platelet indicators were measured in the clinical effective nephritic syndrome patient＆#39;s condition analysis,and the formation of blood clots diagnosis and clinical treatment and prognosis has a greater value.