血液稀释疗法联合低分子肝素治疗短暂性脑缺血发作的临床观察

The Nursing Experience in the Treatment of Ransient Ischemic Attack by Hemodilution Combination of Low Molecular Heparin

目的:观察血液稀释联合低分子肝素治疗短暂性脑缺血发作(TIA)的可行性。方法:将72例TIA病人随机分成两组,治疗组给予低分子右旋糖苷250ml静滴,同时皮下注射低分子肝素钙5000u,2次/d,连用10d;对照组按医嘱常规治疗。治疗10d后,进行临床疗效评定及化验指标观察。结果:治疗组总有效率为93.75%,对照组总有效率为76.66%,两组比较差异有统计学意义(P<0.05)。治疗组治疗后血小板计数、全血高切黏度、血浆黏度均较治疗前、治疗后对照组明显降低,差异有统计学意义(P<0.05)。结论:血液稀释疗法联合低分子肝素更有利于阻止TIA患者病情进展、促进神经功能恢复,而且安全、可靠。

Objective： To observe the clinical curative effect of hemodilution combination of low molecular heparin in the treatment of transient ischemic attack（TIA）. Methods：72 cases with TIA were randomly divided into two groups.The treatment group were intravenous drip injected with 250ml low molecular dextran once a day,and subcutaneously injected with 5000iu low molecular heparin twice a day for 10 days.The control group was conventional treament. after treatment 10 day, assessment of clinical efficacy and laboratory indicators was observed. Results：The prostecdtive efficacy of the treatment group （totai effective was 93.75%） was better than that of the control group （totai effective was 76.66%）,and the significant effective power of nervous functional rehabilitation in the treatment group was much higher than that of the control group（P〈0.05）.The after treatment of treatment group, the platelet count, high shear blood viscosity, plasma viscosity than that before treatment, and control group after treatment was significantly decreased, the difference was statistically significant （P〈0.05）.Conclusion：The treatment of hemodilution combination of low molecular heparin was favorable for stopping the advancement of stroke and promoting the recovery of nerves function.It was safe and suitable for the early application.