摘要
目的研究乙型肝炎患者血浆纤维蛋白原及血浆D-二聚体水平的变化。方法以Clauss法测定血浆纤维蛋白原,免疫比浊法测定D-二聚体定量水平。分别检测125例乙型肝炎患者及68例正常人血浆纤维蛋白原和D-二聚体的含量。结果与正常对照组比较,乙型肝炎患者纤维蛋白原和D-二聚体定量水平有极显著性差异(P<0.001)。结论乙型肝炎患者体内呈现不同程度的继发性纤溶,提示联合血浆纤维蛋白原和D-二聚体检测能反映乙型肝炎患者肝功能受损的凝血变化,对预后的判断有良好的临床应用价值。
Objective To study the changes of plasma fibrinogen and D-dimer in patients with hepatitis B. Method plasma fibrinogen were measured by Clauss,D-dimer were quantitated by immunoassay turbidimetry ,the two experiment were determined in 125 patients with hepatitis B and 68 normal controls. Result There were significant differences between the patients group and normal controls group ,such as the level of plasma fibfinogen and D-dimer（P〈0.001）. Conclusion Different degree of hyperfibrinolysis exists in hepatitis B ,indicating plasma fibrinogen and D -dimmer is clinically useful for judgement of the outcome prediction of the patients with hepatitis B.
出处
《中国医药指南》
2014年第10期31-32,共2页
Guide of China Medicine
