左氧氟沙星不良反应及合理使用

Analysis of adverse drug reaction in- duced by levofloxacin

目的：通过对我院左氧氟沙星在临床应用过程中产生ADR的病例进行分析，以期为左氧氟沙星的临床安全合理用药提供参考．方法：以我院2010—2014年间涉及左氧氟沙星不良反应的病例为第一手资料，对左氧氟沙星引起的不良反应病例以年龄、性别、给药途径、涉及的主要器官、对原患疾病的影响等方面进行统计分析．结果：女性患者多于男性患者，年龄越大，发生概率越高；注射滴注是引起ADR最多的给药途径，ADR涉及的系统以皮肤及其附属系统最多；一般ADR对原患疾病的影响不明显等．结论：加强对左氧氟沙星ADR的认识，合理使用左氧氟沙星，尽量减少ADR的发生．

AIM： Through the analysis of levofloxacin ADR ca ses arising in the clinical application process in our hospital to provide reference for clinical drug safety about levofloxacin. METHODS： We take between 2010 -2014 involving levofloxa cin adverse reactions in our hospital as first-hand information, from age, sex, route of administration, the main behavior in clini- cal, the impact to the original illness to add up and analyze ad verse reactions caused by levnfloxacin. RESULTS： Female pa tients are more than male patients, the greater the age, the higher the probability of occurrence; injection drip route of administration that caused by a maximum of ADR, the skin and its subsid iaries involved in ADR system are the most; in general ADR is not obviously Influence to the original illness. CONCLUSION： Raising awareness about ADR caused by levofloxaein, rational u sing of levofloxacin, minimizing the incidence of ADR.