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胃肠道间质瘤肝转移16例临床分析

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摘要 目的:探讨胃肠道间质瘤肝转移的临床诊治及预后情况,为临床诊治提供依据。方法选取我院2010年2月至2013年2月期间收治的胃肠道间质瘤肝转移患者病例16例临床资料,针对临床检查及病理情况、治疗情况进行回顾性分析。结果同时性肝转移手术者6例,其中3例进行全胃切除加肝右叶不规则切除,胃近端切除加肝左叶规则切除2例,小肠部分切除加转移灶1例。异时性肝转移手术者10例,肝转移灶切除2例,肝左叶规则切除5例,肝右叶规则切除2例,肝右叶不规则切除1例。手术后恢复良好者13例,术后2例发生胆瘘、1例发生肝创面出血经治疗无效死亡。随访时间19~56个月,术后1、2、3年无病生存率为92.2%、52.2%和26.7%。结论胃肠道间质瘤肝转移采取转移灶切除是相对安全的,可获得较长生存期,临床疗效较好。
作者 胡志平
出处 《中国医药指南》 2014年第9期110-111,共2页 Guide of China Medicine
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  • 1Singer S, Rubin BP, Lux ML, et al. Prognostic value of KIT mutation type, mitotic activity, and histologic subtype in gastrointestinal stromal tumors[J]. J Clin Oneol, 2002,20(18):3898-3905.
  • 2Trent JC, Benjamin RS. New developments in gastrointestinal stromal tumor[J]. Curr Opin Oncol, 2006,18(4):386-395.
  • 3Kindblom LG, Remotti HE, Aldenborg F, et al. Gastrointestinal pace maker cell tumor (GIPACT): gastrointestinal stromal tumors show phenotyplc characteristics of the interstitial ceils of Cajal[J]. Am J Pathol, 1998,152:1259-1269.
  • 4Heinrich MC, Corless CL,Anette Duensing, et al. PDGFRA activating mutations in gastrointestinal stromal tumors[J]. Science, 2003,299: 708-710.
  • 5Bauer S, Corless C, Heinrich MC, et al. Response to imatinib mesylate of a gastrointestinal stromal tumors with very low expression of KIT[J]. Cancer Chemo Phamacol, 2003,51:261-265.
  • 6Dematteo RP, Heinrich MC, EL-Rifai WM, et al.Clinical management of gastrointestinal stromal tumors: before and after STI-571 [J]. Hum Pathol, 2002,33:466-477.
  • 7Fletcher CD, Berman JJ, Corless C, et al. Diagnosis of gastrointestinal stromal tumors: A consensus approac [J]. h. Hum Pathol, 2002,33 (3) :459-465.
  • 8Mazur MT, Clark HB. Gastric stromal tumors. Reappraisal of histogene- sis. Am J Surg Pathol, 1983,7:507-519.
  • 9Joensuu H. Risk stratification of patients diagnosed with gastrointestinal stromal tumor. Hum Patho1,2008,39 : 1411-1419.
  • 10Miettinen M, Majidi M, Lasota J. Pathology and diagnostic criteria of gastrointestinal stromal tumors (GISTs) :a review. Eur J Cancer, 2002, 38(Suppl 5) :S39-51.

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