液晶材料中间体-4-(反式,反式-4-丙基双环己基)苯乙酮的合成

The Synthesis of 4-(Trans, trans-4-propyl-bicyclohexyl) Acetophenone-an Intermediate of Liquid Crystal Material

液晶材料目前的制备方法复杂,市场上成熟的原料合成路线基本没有。要制备性能优异的、使用广泛的液晶材料需要多步反应。以市场中常见的4-(反式,反式-4-丙基双环己基)苯为原料,经傅克酰基化反应得到目标产物。主要考察了4-(反式,反式-4-丙基双环己基)苯乙酮的合成条件,如酰基化反应溶剂、酰基化反应温度、酰基化反应时间及水解反应溶剂四个条件的影响,确定了合成反应的最佳条件。并采用红外光谱和核磁共振方法确证了目标产物。

The method for preparing liquid crystal material is not easy at present. There is no mature synthetic method about it in any industries. The muhi-step reaction is needed to get liquid crystal material with better property and wide applications. The common 4-（trans, trans-4-propyl-4- bicyclohexyl） benzene was used as substrates to produce the 4-（trans, trans-4-propyl-bieyclohexyl） acetophenone by Friedel-Crafts acetylation. The synthetic conditions for 4-（trans,trans-4-propyl-bicyclohexyl） acetophenone was studied, such as the effects of reaction solvents, reaction temperature and time and solvents in hydrolysis. The best reaction conditions were obtained. And the product was confirmed by FT-IR and H-NMR.