摘要
目的:探讨鼻咽黏膜DWI分型对于诊断鼻咽恶性病变的价值。方法:根据鼻咽黏膜显示的对称性、黏膜最高信号与脊髓信号的比较,91例鼻咽黏膜DWI图像分为4型,Ⅰ型(低信号对称型)15例、Ⅱ型(低信号不对称型)5例、Ⅲ型(高信号对称型)32例、Ⅳ型(高信号不对称型)39例。将分型结果与定性结果进行比较,探讨各型表现与鼻咽恶性病变发生的关系。结果:Ⅰ型中未发现恶性病变,Ⅱ型发现1例恶性病变,Ⅰ型与Ⅱ型之间无显著性差异,合并为"Ⅰ型+Ⅱ型"。Ⅲ型发现恶性病变21例、Ⅳ型发现37例。整体上各型之间有显著性差异(χ2=46.848,P<0.001)。"Ⅰ型+Ⅱ型"与Ⅲ型、"Ⅰ型+Ⅱ型"与Ⅳ型、Ⅲ型与Ⅳ型之间均存在显著性差异(χ2=18.533,P<0.001;χ2=46.579,P<0.001;χ2=10.052,P=0.002)。结论:当DWI图像上鼻咽黏膜表现为Ⅲ型或Ⅳ型时,临床应高度怀疑恶性病变的可能;若表现为Ⅰ型或Ⅱ型时,临床上不应盲目诊断为恶性,需充分结合其他辅助资料分析。
Objective: This study aims to investigate the importance of nasopharyngeal mucosa typing in the diffusion weighted imaging (DWI) for the diagnosis of nasopharyngeal malignant lesions. Methods: Based on the symmetry of nasopharyngeal mucosa and on the comparison between the highest mucosa signal and the spinal cord signal, 91 cases of nasopharyngeal mucosa DWI images were divided into four types, namely, type I (low signal and symmetry, 15 cases), type 11 (low signal and asymmetry, five cases), type Ⅲ(high signal and symmetry, 32 cases), and type IV (high signal and asymmetry, 39 cases). The typing and qualitative results were compared to investigate the relationship between the typing and nasopharyngeal malignant lesions. Results: Malignant lesions were not found in type I, and only one case of malignant lesions was found in type II. No significant differences were observed between types I and Ⅱ; therefore, these types were merged into "type I + 11 ." A total of 21 and 37 cases with malignant lesions were found in types I I1 and IV, respectively. Significant differences were generally found among these types (X2=46.848, P=0.000), that is, between "type I + II" and type HI, "type I + II" and type IV, as well as between types Ⅲ and IV (X2= 18.533, 46.579, 10.052, P=-0.000, 0.000, and 0.002, respectively). Conclusion: The DWI images of the nasopharyngeal mucosa showed that suspected malignant lesions should be found in type Ⅲ or IV. If found to be type I or II, such lesions should not be clinically considered malignant. Other auxiliary data are needed for diagnosis.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
2014年第6期394-398,共5页
Chinese Journal of Clinical Oncology
关键词
弥散加权成像
鼻咽肿瘤
诊断影像学
diffusion weighted imaging, nasopharyngeal neoplasm, diagnostic imaging