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万古霉素耐药肠球菌属分子特征及遗传背景的研究 被引量：11

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摘要 1988年,英国报道了万古霉素耐药肠球菌（vancomycin resistance Enterococcus,VRE）,随后其他欧洲国家和美国也相继检出VRE.目前VRE已成为重要医院内感染病原菌.美国卫生感染监管系统（National Nosocomial Infections Surveillance,NISS）将其列为引起院感的第二大病原菌[1].国内VRE分离率一般低于国外,但近年VRE的感染呈上升趋势,而某些医院也有暴发流行的报道[2].
作者 孙明月 李丽 张蓓 陈中举 田磊 汪玥 刘彩林 欧国平 徐令清 孙自镛
机构地区 华中科技大学同济医学院附属同济医院检验科
出处 《中华检验医学杂志》 CAS CSCD 北大核心 2014年第3期210-212,共3页 Chinese Journal of Laboratory Medicine
关键词 万古霉素耐药肠球菌 遗传背景 分子特征 肠球菌属 Infections 感染病原菌 VRE 欧洲国家
分类号 R378.1 [医药卫生—病原生物学]
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参考文献22

  • 1Schaberg DR, Culver DH, Gaynes RP. Major trends in the microbial etiology of nosocomial infection[ J]. Am J Med, 1991, 91 : 72S-75S.
  • 2Zheng B, Tomita H, Xiao YH, et al. The first molecular analysis of clinical isolates of VanA-type vaneomyein-resistant Enterococcus faecium strains in China's Mainland [ J ]. Lett Appl Microbiol, 2007, 45: 307-312.
  • 3Lebreton F, Depardieu F, Bourdon N, et al. D-Ala-d-Ser VanN- type transferable vancomyein resistance in Enterococcus faecium [ J]. Antimicrob Agents Chemother, 2011, 55: 4606-4612.
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二级参考文献20

  • 1Patel R.Clinical impact of vancomycin-resistant enterococci.J Antimicrob Chemother,2003,51 Suppl3:iii13-21.
  • 2Goossens H,Jabes D,Rossi R,et al.European survey of vancomycin-resistant enterococci in at-risk hospital wards and in vitro susceptibility testing of ramoplanin against these isolates.J Antimicrob Chemother,2003,51 Suppl3:iii5-21.
  • 3Cetinkaya Y,Falk P,Mayhall CG.Vancomycin-resistant enterococci.Clin Microbiol Rev,2000,13:686-707.
  • 4Chang S,Sievent DM,Hageman JC,et al.Infection with vancomycin-resistant Staphylococcus aureus containing the vanA resistance gene.N Engl J Med,2003,348:1342-1347.
  • 5Hashimoto Y,Tanimoto K,Ozawa Y,et al.Amino acid substitutions in the VanS sensor of the VanA-type vancomycinresistant Enterococcus strains result in high-level vancomycin resistance and low-level teicoplanin resistance.FEMS Microbiol Lett,2000,185:247-254.
  • 6Lauderdale TL,McDonald LC,Shiau YR,et al.Vancomycinresistant enterococci from humans and retail chickens in Taiwan with unique VanB phenotype-VanA genotype incongruence.Antimicrob Agents Chemother,2002,46:525-527.
  • 7Song JH,Ko KS,Oh WS,et al.High frequency of vancomycinresistant Enterococcus faecium isolates with VanB phenotype and VanA genotype in Korean hospitals.Diagn Microbiol Infect Dis,2006,56:401-406.
  • 8Gu L,Cao B,Liu Y,et al.A new Tn1546 type of VanB phenotype-VanA genotype vancomycin-resistant Enterococcus faecium isolates in China's Mainland.Diagn Microbiol Infect Dis,2009,63:70-75.
  • 9Kariyama R,Mitsuhata R,Chow JW,et al.Simple and reliable multiplex PCR assay for surveillance isolates of vancomycinresistant enterococci.J Clin Microbiol,2000,38:3092-3095.
  • 10Yu HS,Seol SY,Cho DT.Diversity of Tn1546-like elements in vancomycin-resistant enterococci isolated from humans and poultry in Korea.J Clin Microbiol,2003,41:2641-2643.

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二级引证文献66

中华检验医学杂志
2014年 第3期

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