糠酸莫米松鼻喷剂和孟鲁司特钠联合治疗儿童腺样体肥大的疗效观察

The treatment of adenoidal hypertrophy by mometasone furoate combined with montelukast

目的探讨儿童腺样体肥大的非手术治疗方法及其疗效。方法联合使用糠酸莫米松鼻喷剂和孟鲁司特钠治疗儿童腺样体肥大30例,按照腺样体大小分为轻度12例、中度11例、重度7例三组,同时按照有无变应性鼻炎分为伴变应性鼻炎组19例和不伴变应性鼻炎组11例。患者的症状评分根据Carlos O'Connor-Reina的家长调查问卷获得。结果轻度组中有效率91.7%(11/12),中度组有效率63.6%(7/11),重度组有效率14.3%(1/7)。伴变应性鼻炎组有效率73.7%(14/19),不伴变应性鼻炎组有效率36.4%(4/11)。结论糠酸莫米松鼻喷剂联合孟鲁司特钠是非手术治疗腺样体肥大一个较好的方法 ,但各组效果不一。轻度腺样体肥大效果较好,重度腺样体肥大效果较差。对于伴有变应性鼻炎的腺样体肥大治疗效果明显优于不伴有变应性鼻炎的。

Objective To explore the non-surgical treatment and efficacy of adenoidal hypertrophy in children. Methods 30 cases of adenoidal hypertrophy were treated with mometasone furoate （Nasonex） combined with montelukast （Singulair）. All patients were divided into three groups （mild, moderate, severe） according to the size of adenoid. They were also divided into two groups according to the presence or absence of allergic rhinitis. Symptom scores of patients were acquired by Carlos O＆#39;Connor-Reina questionnaire. Results The efficiency in the mild group was 91.7% （11/12）, in the moderate group was 63.6% （7/11） and in the severe group was 14.3% （1/7）. The efficiency of adenoidal hypertrophy with allergic rhinitis group was 73.7% （14/19） and not with allergic rhinitis group was 36.4% （4/11）. Conclusion Mometasone furoate combined with montelukast is a good non-surgical treatment of adenoidal hypertrophy. However, the effect is different for different patients. The efficiency is better for mild and moderate adenoid hypertrophy but poor for severe group. At the same time, the efficiency is better for adenoidal hypertrophy with allergic rhinitis than not with allergic rhinitis.