帕金森病非运动症状及药物治疗研究进展

Non-motor Symptoms of Parkinson's Disease

帕金森病(Parkinson’s disease,PD)是以运动功能异常和非运动症状为特征的中枢神经退行性疾病。非运动症状包括睡眠障碍、神经精神病学障碍、认知功能障碍、自主神经系统障碍、胃肠道功能紊乱和感觉症状等。由于缺乏足够的认识和重视,这些症状常被忽视或误诊,严重影响到帕金森病患者的生活质量。该文对帕金森病非运动症状的表现及治疗进展做一综述。

Parkinson’s disease （PD） is a progressive,disabling neurodegenerative disorder with onset of motor and non-motor features. Non-motor symptoms include sleep disorders, neuropsychiatric symptoms,cognitive impairment,autonomic dysfunction,gastrointestinal and sensory symptoms. These symptoms are important factors related quality of life affected PD patients. This article will provide an overview of the non-motor symptoms of PD and their treatment options.