天津市不同人群2594例病毒性乙型肝炎感染/免疫状况流行病学调查分析

An epidemiological survey of the prevalence of 2 594 cases with viral hepatitis B infection in different populations

目的 了解天津市不同人群病毒性乙型肝炎的感染/免疫状况,为制订防治对策提供科学依据.方法 采用不等比例分层整群抽样抽取1 ～59岁人群2 594例,用ELISA方法对其进行乙型肝炎病毒感染标志物检测.结果 2 594例中,HBV感染/免疫检出率为51.54％,HBs-Ag、抗-HBs和抗-HBc阳性率分别为2.62％、46.72％和10.60％.结论 HBV感染/免疫、HBs-Ag及抗-HBc阳性率均显著低于天津市1992年的调查结果,抗-HBs阳性率显著高于1992年结果,这与近年来实施以接种乙肝疫苗为主的综合措施有关.

Objective To find out the present situation of hepatitis B infection or immunity in Tianjin city, and to provide the scientific basis for the hepatitis B control and prevention. Methods 2 594 samples were selected with the methods of different proportionate stratified and cluster sampling, and the hepatitis B infection markers were detected by ELISA. Results The positive rates of HBsAg, anti-HBs, anti-HBc and HBV were 2.62% ,46.72%, lO. 60% and 51.54%. Conclusion Compared with the results in 1992,the positive rates of HBsAg,anti-HBc and HBV were decreased significantly, while the positive rate of anti-HBs increased significantly, which ascribed to the comprehensive measure with the vaccination against hepatitis B as a main strategy for control hepatitis B.