综合护理干预减轻急性白血病化疗患者胃肠道反应的研究

Study of comprehensive nursing intervention on reducing gastrointestinal reaction induced by chemotherapy in patients with acute leukemia

目的探究在化疗期间实施综合护理干预对急性白血病患者胃肠道反应的改善效果。方法选取2010年7月至2012年12月间收治的78例急性白血病患者,采用随机数字表法分为研究组和对照组,每组39例。对照组患者采取常规护理,研究组患者采取综合护理。记录两组患者在化疗后1周末恶心、呕吐程度,并比较两组患者胃肠道反应发生率。结果研究组患者在化疗不同时间段内胃肠道反应发生率低于对照组,差异有统计学意义(P<0.05)。研究组患者恶心、呕吐程度均低于对照组,差异有统计学意义(P<0.05)。结论综合护理干预能减轻急性白血病化疗患者在的胃肠道反应,提高患者对化疗的耐受性。

Objective To explore the influence of comprehensive nursing intervention on patients with acute leukemia and gastrointestinal reaction. Methods 78 cases with acute leukemia were selected in the intensive care unit of our hospital from July 2010 to December 2012, and divided into study group and control group （39 cases respectively） using the method of random digits table. The control group received routine nursing care, and the study group comprehensive nursing. Degree of nausea and vomiting of two groups were recorded in a weekend after chemotherapy, and the occurrence rates of gastrointestinal tract re- action were compared. Results The study group in different periods of chemotherapy gastrointestinal tract was lower than that of the control group, and the difference was statistically significant （ P 〈 0. 05 ）. Nausea and vomiting of the study group was higher than that of control group, and the difference was statistically significant （P 〈 0. 05）. Conclusions The comprehensive nursing intervention can reduce the gastrointestinal reaction in patients with acute leukemia during chemotherapy, and obtain satisfactory clinical effect.