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全皮下植入式心律转复除颤器——仅仅是权宜之举? 被引量:3

An Entirely Subcutaneous Implantable Cardioverter-Defibrillators——Expedient Measure?
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摘要 植入式心脏转复除颤器(ICD)是预防心脏性猝死最重要的手段。尽管电极导线设计在不断创新,功能逐渐完善,但静脉植入电极导线仍存在一定的风险和相关并发症,三尖瓣病变有时使得电极导线难以植入,而植入的电极导线亦会发生断裂、脱位和穿孔。需要拔除或导线故障需要更换时往往带来额外风险,甚至导致死亡。全皮下植入ICD适合不需要起搏支持的ICD适应证患者,其安全有效性已得到越来越多的证实。 Implantable cardioverter-defibrillator (ICD) is an established therapy for the prevention of death from ventricular arrhyth- mia. Conventional ICD rely on transvenous leads for cardiac sensing and defibrillation. Complications of defibrillator implantation have been associated mainly with transvenous lead insertion and have included pneumothorax, hemothorax, and cardiac tamponade. Moreover, failed leads often require removal, a procedure that is associated with substantial morbidity and mortality. Subcutaneous ICD (S-1CD) is suitable in patients without an indication for antibradycardia pacing or cardiac resynchronization therapy and the efficacy and safety of the S-ICD sys- tem for the treatment of life-threatening ventrieular arrhythmias were supported by clinical trial findings.
作者 田颖 刘兴鹏
出处 《心血管病学进展》 CAS 2014年第2期129-132,共4页 Advances in Cardiovascular Diseases
基金 国家自然基金(81370293 81100125) 首都医学发展专项(首发2011-2003-4) 国际科技合作与交流专项(S2011ZR0197)
关键词 植入性心脏转复除颤器 皮下 安全性 有效性 implantable cardiac defibrillator subcutaneous efficacy safety
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  • 1Lloyd-Jones D, Adams RJ, Brown TM, et al. Executive summary: heart dis- ease and stroke statistics-2010 update: a report fi'om the American Heart Asso- ciation[J]. Circulation, 2010, 121(7): 948-954.
  • 2Hill JA, Olson EN. Cardiac plasticity [ J ]. N Engl J Med, 2008,358 ( 13 ) : 1370-1380.
  • 3Kehat 1, Davis J, Tiburcy M, et al. Extracellular signal-regulated kinases 1 amt 2 regulate the balance between eccentric and concentric cardiac growth[ J]. Circ Res,2011,108(2) :176-183.
  • 4Shen Y, Rampino MA, Carroll RC, et al. G-protein-mediated inhibition of the Trp channel TRPMI requires the GI33, dimer [ J ]. PNAS, 2012, 109 ( 22 ) : 8752-8757.
  • 5Watari K, Nakaya M, Kurose H. Multiple functions of G protein-coupled recep- tar kinases [ J]. J Mol Signal,2014,9 ( 1 ) : 1.
  • 6Roosing S, Collin RW, den Hollander AI, et al. Prenylation defects in inherited retinal diseases[J]. J Med Gene,2014,51 (3) :143-151.
  • 7Zhang Y, Matkovich SJ, Duan X, et al. Nuclear effects of G-protein receptor kinase 5 on histone deacetylase 5-regulated gene transcription in heart failure [J]. Circ Heart Fail,2011,4(5) :659-668.
  • 8Vinge LE,Raake PW, Koch WJ. Gene therapy in heart failure [ J ]. Circ Res, 2008,102(12) : 1458-1470.
  • 9Penela P, Nogurs L, Mayor F Jr. Role of G protein-coupled receptor kinases in cell migration[ J ]. Curr Opin Cell Biol,2014,27 : 10-17.
  • 10Woodall MC, Ciccarelli M, Woodall BP, et al. G protein-coupled receptor ki- nase 2 : a link between myocardial contractile function and cardiac metabolism [J]. Circ Res,2014,114(10) :1661-1670.

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