摘要
CA125在充血性心力衰竭患者中显著增高,可作为诊断心力衰竭的新型标志物,是继X射线、多普勒超声心动图及钠尿肽之外对心力衰竭诊断的补充。目前研究表明,血清CA125含量具有以下特点:在心力衰竭患者中显著升高;与脑钠尿肽具有相关性,可作为心力衰竭预后的指标,为临床医生提供指导。现就以上特点做一综述。
Serum levels of carbohydrate antigen 125 (CA-125) have been found to be significantly higher in patients with chronic heart failure (CHF). This increase in CA-125 levels in CHF patients could make CA-125 a viable tool in the diagnostic arsenal for potential heart failure patients. Current research has shown that serum levels of CA-125 indicate : ( 1 ) a significant increase is associated with patients with heart failure; (2) it is associated with brain natriuretic peptide; (3) it can be used as a potential prognostic marker. All these charac- teristics can be used to provide guidance for clinicians. This article reviews the characteristics of CA-125 and how it can be used as a diag- nostic tool.
出处
《心血管病学进展》
CAS
2014年第2期193-196,共4页
Advances in Cardiovascular Diseases
关键词
心力衰竭
肿瘤标志物
CA125
heart failure
tumor markers
carbohydrate antigen 125