心房颤动导管消融联合肾交感神经消融——心房颤动合并高血压治疗的新策略?

Atrial Fibrillation Ablation Combined with Renal Sympathetic Nerve Ablation——A New Treatment Strategy?

心房颤动是临床上最常见的一种心律失常,它可以影响血流动力学和增加脑卒中的风险。近年来心房颤动导管消融发展迅速,但是导管消融治疗心房颤动仍可能复发房性心律失常,目前单纯导管消融治疗心房颤动长期维持窦性心律的成功率还不尽如人意。肾交感神经消融通过抑制交感神经系统及肾素-血管紧张素-醛固酮系统活性从而达到治疗顽固性高血压的目的,现已成为一种有效、安全的新型手术方法。原发性高血压、心房颤动和交感神经系统三者之间有着密不可分的关系,肾交感神经消融可能通过抑制交感神经系统和肾素-血管紧张素-醛固酮系统活性减少心房颤动复发,也许将会成为心房颤动合并高血压治疗的新策略。现就导管消融联合肾交感神经消融治疗心房颤动的相关内容进行综述。

Atrial fibrillation is the most common arrhythmia which can affect haemodynamics and increase the risk of stroke. In recent years, atrial fibrillation catheter ablation has been developing rapidly. On the other hand, patients who have undergone treatment with atrial fibrillation catheter ablation are likely to have a recurrence of atrial arrhythmias. Therefore, the success rate of the catheter ablation to main- tain the sinus rhythm is not satisfactory. Renal sympathetic nerve ablation is a new therapeutic method for treating resistant hypertension. This is done by the inhibition of the sympathetic nervous system and the renin-angiotensin-aldosterone system. This method has already prov- en to be safe and effective. The success of this method also supports the fact that primary hypertension, atrial fibrillation, and sympathetic nervous system all interact with each other. So, renal sympathetic nerve ablation may provide a new treatment option for patients with both atrial fibrillation and hypertension. This paper reviews research related to atrial fibrillation ablation combined with renal sympathetic nerve ablation.