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碳青霉烯酶基因型的研究进展 被引量：10

Progess about carbapenemase genotypes
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摘要 碳青霉烯类抗菌药物具有广泛的抗菌活性,是治疗革兰阴性杆菌感染的一线药物。随着应用的增加,耐药性的问题日益严重。碳青霉烯酶是目前发现肠杆菌科细菌对碳青霉烯类抗菌药物耐药的主要机制。准确快速检测这些耐药基因是控制其传播的关键。本研究对碳青霉烯酶基因型的研究进展进行综述。 Carbapenem is a new β-1actam antibiotic w ith broad anhmmroblal spectrum and resistance to β-1acta- mase hydrolysis, which has been the first choice to treat gram negtive bacillus. With the increase of application, the resistance is more serious. Carbapenem takes part in the major mechanism of carbapenem resistance in enter- obacteriaceae. It is important to accurate these resistance genes in controlling their spread. In this article, the re- search progress about carbapenemase genetype which was reviewed.
作者 杨莉 张红岩
机构地区 滨州市人民医院检验科
出处 《中国微生态学杂志》 CAS CSCD 2014年第3期366-368,共3页 Chinese Journal of Microecology
关键词 碳青霉烯酶 基因型 耐药性 Carbapenemase Gene types Antibiotic resistance
分类号 R378.992 [医药卫生—病原生物学]
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参考文献22

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共引文献63

同被引文献108

  • 1冯娇,殷喆,邱业峰,杨慧盈,杨文慧,王洁,周冬生,高英杰.产IMP酶4种病原细菌的检测及其耐药性[J].中国兽医学报,2015,35(5):722-726. 被引量：1
  • 2刘文静,王瑶,刘勇,赵旺盛,孙自镛,倪语星,孙宏莉,徐英春,谢秀丽,王辉,陈民钧.比阿培南等3种碳青霉烯类抗生素的体外抗菌活性[J].中国感染与化疗杂志,2010,10(6):468-471. 被引量：29
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引证文献10

二级引证文献59

中国微生态学杂志
2014年 第3期

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