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孕妇妊娠期糖尿病孕期血脂评估的临床价值 被引量:13

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摘要 目的:分析孕妇妊娠期糖尿病孕期血脂水平变化,探讨血脂评估在孕妇妊娠期糖尿病的临床价值。方法:选择在该院门诊就诊的妊娠期糖尿病孕妇(观察组)250例和正常健康孕妇(对照组)100例,分别于孕12—20周、24—32周时抽取空腹静脉血测定高密度脂蛋白(HDL)、低密度脂蛋白(LDL)、载脂蛋白AI(APOAI)、血浆总胆固醇(TC)、甘油三脂(TG)、载脂蛋白B(APOB)、脂蛋白A(LPA)。结果:两组的TG、TC、APOB、APOAI、LDL值随着孕周的增加而显著升高,观察组妊娠晚期的LPA值比妊娠中期时明显升高,差异有统计学意义(t=3.834,P=0.0001)。两组间妊娠中、晚期血脂指标比较,观察组的TG、LDL、APOB值明显高于对照组,差异有统计学意义(P值均〈0.01),两组的TC、HDL、APOAI、LPA在妊娠中期比较时差异无统计学意义(P值均〉0.05),但观察组的HDL、APOAI值在妊娠晚期明显低于对照组(P值均〈0.01),LPA、TC值明显高于对照组。结论:孕妇妊娠期糖尿病在妊娠中、晚期的血脂水平普遍高于正常健康孕妇,特别是TG、LDL、APOB值;妊娠期糖尿病孕妇的脂代谢异常常较正常健康孕妇更加明显、早期,应尽早制定饮食计划,合理搭配膳食,减少因糖尿病带来的母婴危害。
作者 吴蔚
出处 《中国妇幼保健》 CAS 北大核心 2014年第11期1682-1684,共3页 Maternal and Child Health Care of China
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