综合检测方式诊断早期宫颈癌及癌前病变的临床价值

Clinical value of combined detection method in diagnosis of early cervical cancer and cervical precancerous lesion

目的:探讨综合检测方式诊断早期宫颈癌及癌前病变的临床价值。方法:回顾性分析经阴道彩色多普勒超声(TVCDS)和阴道镜诊断的177例早期宫颈癌及癌前病变患者的检查结果,并与病理检查结果进行比较。同时选取门诊健康体检者80例作为对照组,比较癌前病变、宫颈癌、健康对照者的阻力指数(RI)和收缩期峰值血流速度(PSV)。结果:宫颈癌及癌前病变患者RI水平均低于对照组(P<0.05),宫颈癌患者RI水平均低于癌前病变患者(P<0.05)。宫颈癌及癌前病变患者PSV水平均高于对照组(P<0.05),宫颈癌患者PSV水平高于癌前病变患者(P<0.05)。阴道镜与TCVDS联合阴道镜诊断宫颈癌、癌前病变准确率分别是91.43%、98.10%和97.22%、100.00%,均高于TCVDS(P<0.05)。结论:TVCDS联合阴道镜可以显著提高宫颈癌及癌前病变诊断准确率,具有较高的应用价值。

Objective： To explore the clinical value of comprehensive detection method in diagnosis of early cervical cancer and cervical precancerous lesion. Methods： The detection results of transvaginal color Doppler sonography （TVCDS） and colposcopic diagnosis for 177 patients with early cervical cancer and cervical precancerous lesion were analyzed retrospectively, and then the results were compared with pathological results. At the same time, 80 healthy women receiving healthy physical examination in outpatient department were selected as control group; the values of resistance index （RI） and peak systolic velocity （PSV） in cervical precancerous lesion group, cervical cancer group, and control group were compared. Results： RI levels in cervical cancer group and cervical precancerous lesion group were statistically significantly lower than that in control group （ P 〈 0. 05 ）, RI level in cervical cancer group was statistically significantly lower than that in cervical precancerous lesion group （P 〈 0. 05 ） ; PSV levels in cervical cancer group and cervical precancerous lesion group were statistically significantly higher than that in control group （ P 〈 0. 05 ）, PSV level in cervical cancer group was statistically significantly higher than that in cervical precancerous lesion group （ P 〈 0. 05 ） ; the accurate rates of colposcopy and colposcopy combined with TCVDS in diagnosis of cervical cancer and cervical precancerous lesion were 91.43%, 98. 10% and 97. 22%, 100. 00%, respectively, which were statistically signifi- cantly higher than those with TCVDS （ P 〈 0.05 ） . Conclusion ： TVCDS combined with colposeopy can significantly improve the diagnostic accurate rates of cervical cancer and cervical precursor lesion, which has relatively high application value.