静脉输液反应诱发老年患者心电图、心肌酶及cTnI改变初探

Change of ECG, myocardial enzyme and cTnI in elderly patients due to intravenous infusion reaction

目的 观察老年患者输液反应时心电图、心肌酶及肌钙蛋白Ⅰ（cTnI）变化情况.方法 对我院2010年6月至2012年6月出现输液反应的62例老年患者（输液反应组）进行心电图、血清心肌酶和cTnI检测,并以60例无输液反应老年患者作为对照组进行比较.结果 输液反应组患者心电图异常率高于对照组（P＜0.05或P＜0.01）;血清天冬氨酸转移酶（AST）、乳酸脱氢酶（LDH）、肌酸激酶（CK）、肌酸激酶同工酶（CK-MB）和cTnI水平及阳性例数亦明显高于对照组（P＜0.01）;输液反应组患者cTnI异常率高于其他心肌酶指标.结论 静脉输液反应可诱发老年患者潜在性心肌损伤,导致心电图、心肌酶及cTnI发生改变,应加强检测,尽早发现及时治疗.

Objective To observe the changes of ECG,myocardial enzyme and cardiac troponin Ⅰ （cTnI） in elderly patients due to the reaction of intravenous infusion.Methods ECG,myocardial enzyme and cTnI of 62 elderly patients with intravenous infusion reaction in our hospital from June 2010 to June 2012 were detected,and 60 elderly patients with non-infusion reaction were selected as control group for comparison.Results The abnormal ECG rate of patients with intravenous infusion reaction was higher（P＜0.05 or P＜0.01）.The levels and positive numbers of serum aspartic acid transferase（AST）,lactate dehydrogenase（LDH）,creatine kinase（CK）,creatine kinase isoenzyme （CK-MB） and cTnI were significantly higher（P＜0.01）.The abnormal rate of cTnI was significantly higher than those of cardiac enzymes.Conclusion Intravenous infusion reactions could induce potential myocardial damage in elderly patients that cause ECG,cardiac enzymes and cTnI change.we should enhance detection,early detection and timely treatment.