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apoB/apoA1值与冠心病相关性研究进展 被引量：10

Research Overview on Relationship Between ApoB / apoA1 Ratio and Coronary Heart Disease
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摘要 冠状动脉粥样硬化性心脏病是威胁人类健康的主要疾病之一。血脂代谢异常是冠心病的主要发病机制,作为LDL-C、HDL-C的载脂蛋白,apoB和apoA1是目前研究的热点。冠心病患者冠脉病变程度与血清中apoB呈正相关,与apoA1成负相关,高apoB、apoB/apoA1,低apoA1水平是冠心病发生的危险因素,而且apoB/apoA1值对冠心病风险的预测优于其它胆固醇比值,具有广阔的临床应用前景。 Coronary heart disease has been one of the most serious diseases threatening human health. Abnormal lipid metabolism is the main pathogenesis of coronary artery disease. As apolipoprotein of LDL - C and HDL - C, apols, apoAl are the research focus. The degree of coronary artery stenosis is positively related to apoB and negatively correlated to apoAl. High apols , apoBI apoAl and low apoAl levels are the risk factors for coronary heart disease, and apob/ apoAl ratio is better than other cholesterol ratios on predicting coronary risk, it has a wide prospect of clinical application.
作者 李鹏 王桂云 逯建华
机构地区 内蒙古医科大学 呼伦贝尔市人民医院
出处 《内蒙古医学杂志》 2014年第1期43-45,共3页 Inner Mongolia Medical Journal
关键词 APOB APOA1 冠心病 apoB/apoAl ratio coronary heart disease
分类号 R541.4 [医药卫生—心血管疾病]
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参考文献15

  • 1陆再英,钟南山.内科学[M].第7版.北京:人民卫生出版社,2008.718.
  • 2WaUdius G, Jtmgner I. Apolipoprotein B and apolipoprotein A- I: risk indicators of coronary heart disease and targets for lipid - modifying therapy[J ]. J Intern Med, 2004, 255 (2) : 188.
  • 3Snidenrmn AD, Barter PJ, BaUantyne CM, et al. ApoB versus cholesterol in estimating cardiovascular risk and in guiding thera- py:Report of the thirty person/ten country panel[J]. J Intern Med, 2006, 259(3):247 - 258.
  • 4Benn M. apolipoprotein B levels, AIB alleles, and risk of is- chemic cardiovascular disease in the general population a review [J ]. Atherosclerosis, 2009, 206 (1) : 17 - 30.
  • 5Schlitt A, Blankenberg S, Bickel C, el al. Prognostic value of lipoproteins and their relation to inflammatory markers among pa- tients with coronary artery disease[J]. Int J Cardiol, 2005, 102 (3) : 477.
  • 6walldius G, Jungner I, Aastveit AH, et al. The apo B/ apo A- I Ratio is better than the cholesterol ratios to estimate the balance between the plasma proatherogenic and antiatherogenic lipopro- teins and predict coronary risk[J]. Clin Chem Lab Med, 2004, 42 (12):1 355.
  • 7McQueen M, Hawken S, Wang X, et al. Lipids, lipoprotekns, and apolipoproteins as risk markers aasociated with myocardial in- farction in 52 countries(the inter heart study); a case- control study[J]. Lancet, 2008, 372(9634) :224 - 233.
  • 8Rasouli M, Kiasari AM, Mokhberi V. The ratio of apoB/apoA1, apoB and lipopmtein(a) are the best predictors of stable coronary artery disease[J]. Clin Chem Lab Med, 2006, 44(8): 1 015 - 1 021.
  • 9Goswami B, Rajappa M, MaUika V, et al. APOB/apoA1 ratio: a better discriminator of coronary artery disease risk than other con- ventional lipid ratios in Indian patients with acute myocardial in- farction[J]. Acta Cardiol, 2008, 63(6) : 749 - 755.
  • 10Jungner I, Sniderman AD, Furberg C, et al. Does Low - density lipoprotein size add to atherogenie number in predicting the risk of fatal myocardial infarction[J]. AM J Cardiol, 2006, 97:943 - 946.

二级参考文献23

  • 1郭永和,张维君,周玉杰,赵冬,周志明,张红.冠状动脉造影患者心血管病危险因素与冠状动脉病变程度的相关性分析[J].中华心血管病杂志,2005,33(5):415-418. 被引量：73
  • 2汤涌,黄进,陆治平,杨明智.冠心病患者高密度脂蛋白胆固醇状况分析[J].实用全科医学,2006,4(4):386-387. 被引量：28
  • 3魏建明,白永怿,龚辉,沈伟,张象贤.糖尿病与冠状动脉病变程度的关系(附170例报告)[J].中国临床医学,2006,13(4):545-546. 被引量：2
  • 4中国成人血脂异常防治指南[J].中华心血管病杂志,2007,35(5):390-419. 被引量：5233
  • 5Austen W G,Edwards J E,Frye R L,et al. A reporting system on patients evaluated for coronary artery disease. Report of the Ad Hoc Committee for Grading of Coronary Artery Disease, Council on Cardiovascular Surgery, American Heart Association [ J]. Circulation, 1975,51 (4) :5-40.
  • 6Chobanian A V, Bakris G L, Black H R, et al. Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure[J]. Hypertension ,2003,42 ( 6 ) : 1206-1252.
  • 7Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Report of the expert committee on the diagnosis and classification of diabetes mellitus [ J ]. Diabetes Care,2003,26( 1 ) : S5-20.
  • 8Ross R. Atherosclerosis : an inflammatory disease [ J ]. N Engl J Med,1999,340(2) :115-126.
  • 9Libby P, Ridker P M, Maseri A. Inflammation and atherosclerosis [ J ]. Circulation, 2002,105 (9) : 1135-1143.
  • 10Goraya T Y, Leibson C L, Palumbo P J, et al. Coronary atherosclerosis in diabetes mellitus : a population-based autopsy study[J]. J Am Coll Cardiol,2002,40(5) :946-953.

共引文献53

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引证文献10

二级引证文献70

内蒙古医学杂志
2014年 第1期

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