乳果糖治疗老年慢性功能性便秘的临床疗效

Clinical Effect of Lactulose in the Treatment of Senile Chronic Functional Constipation

为探讨乳果糖口服治疗老年慢性功能性便秘（CFC）的临床疗效，将40例老年CFC患者随机分成观察组和对照组，各20例，对照组口服麻仁丸（每次9g，每天1～2次），观察组口服乳果精（每次15ml，每天3次），两组均以4周为一疗程，比较两组患者临床总有效率及症状缓解率。结果显示，观察组总有效率明显最高于对照组，P〈0．05。两组腹胀、腹痛缓解率比较差异无统计学意义，P〉O．05；但观察组排便困难、食欲不振缓解率明显高于对照组，P〈O．05。结果表明，与麻仁丸相比，乳果糖口服治疗老年CFC更方便，疗效更好，值得临床推广应用。

This study was to explore the clinical effect of lactulose in the treatment of senile chronic rune-ted 4 weeks all in both groups, then the total effective rate and remission rate of symptoms between both groups compared. As results, the total effective rate of observation group was significantly higher than that of control group（ P d0.05）;in the remission rate of burbulence,abdominal pain there was no statistical difference between both groups（ P 0.05）,but the remission rate of difficult defecation,inappetence was significantly higher than that of control group（ P d0.05）. Results show that lactulose in the treatment se- nile CFC is perfect with more convenient, better effect compared with Hemp seed pill, thus worthy to be popularized clinically. Key Words