2012年南阳市疑似预防接种异常反应监测数据分析

Analysis of adverse events following immunization surveillance in Nanyang of 2012

目的:评价2012年南阳市疑似预防接种异常反应(adverse event following immunization,AEFI)监测系统运转情况,探讨监测重点。方法:对2012年南阳市系统上报告的AEFI个案数据进行描述性流行病学分析。结果:2012年南阳市共报告127例个案,其中8个县报告例数不到10例,占61.54%;男性多于女性,性别比为1.89∶1;<1岁年龄组最多,占53.54%;一般反应占98.42%,异常反应占1.57%;百白破疫苗报告例数最多,占51.18%;白破疫苗AEFI发生率最高,为110.24/100万剂;接种后24 h内发生者101例,占79.53%;48 h内报告率和调查率均为100%。结论:全市AEFI监测敏感性尚需提高,低龄儿童、接种后2 d内为监测重点。

Objective ： To evaluate the performance of adverse event following immunization （AEFI）and find the key problem of surveillance system in Nanyang in 2012. Methods： AEFI data from system reported by Nanyang city in 2012 was analyzed by the descriptive epidemiology method. Results： 127 AEFI cases were totally reported in Nanyang in 2012. The reported cases in 8 coun- ties were bellow 10, accounting for 61.54%. More cases occurred in males than females with the ratio of 1.89： 1. Cases aged 〈 1 year were the most, common accounting for 53.54%. 98.42% were presented general reactions after immunization, and 1.57% were rare, serious reactions. 51.18% were caused by the immunization of Diphtheria, Tetanus and Pertussis Combined Vac- cine, Absorbed（DPT）. The highest rate was estimated 110.24/1 000 000 caused by Diphtheria and Tetanus Combined Vaccine（DT）. 101 cases occurred within 24 h after vaccination, account- ing for 79.53%. The reported rate and the investigated rate within 48 h were all 100%. Conclu- sion： The sensitivity of Nanyang AEFI surveillance should be improved. Y＇oung children within 2 days after vaccination are the focus of the AEFI surveillance.